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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases ( NIAID ) "Modeling Host...

  1. Datasets

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Influenza A Experiment IM104 Processed Omics Data Unavailable This Influenza experiment evaluated mouse lung expression after etoposide treatment and infection with a pandemic H1N1 influenza strain. Related Experimental Data BioProject: PRJNA382278 GEO: GSE97555 (mRNA transcriptome response)...

Both highly pathogenic avian influenza virus and Middle East respiratory syndrome coronavirus (MERS-CoV) infections are characterized by severe disease and high mortality. The continued threat of their emergence from zoonotic populations underscores an important need to understand the dynamics of...
The pathogenesis of human Ebola virus disease (EVD) is complex. EVD is characterized by high levels of virus replication and dissemination, dysregulated immune responses, extensive virus- and host-mediated tissue damage, and disordered coagulation. To clarify how host responses contribute to EVD...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EH001 The purpose of this experiment was to evaluate the human patient peripheral blood mononuclear cells (PBMC) response to Zaire Ebola Makona virus infection during the 2013-2016 epidemic in West Africa. Samples were...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile Virus Experiment WLN002 The purpose of this experiment was to evaluate the host response to wild-type West Nile virus infectious clone (WNV-NY99 clone 382) and mutant (WNV-NY99 382 E218A 2 nt) virus infection. Sample data was...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile Virus Experiment WCT001 The purpose of this experiment was to evaluate the host response to wild-type West Nile Virus (WNV; WNV-NY99 382) and WNV-E218A (WNV-NY99 382 E218A 2 nt) mutant virus infection. Sample data was obtained from...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile Virus Experiment WCB001 The purpose of this experiment was to evaluate the host response to wild-type West Nile virus (WNV-NY99 382) and mutant WNV-E218A (WNV-NY99 382 E218A 2 nt) virus infection. Sample data was obtained from mouse...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment IM103 The purpose of this experiment was to evaluate the host response to wild-type Influenza A/Vietnam/1203/2004 (H5N1; "VN1203") virus infection and mock infection. Sample data was obtained for mouse lung tissue...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment IM102 The purpose of this experiment was to evaluate the mouse host response to wild-type Influenza A/Anhui/1/2013 (H7N9; "AH1-WT") virus and mutant viruses NS1-103F/106M ("AH1-F/M") and partially ferret-adapted (...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment IM101 The purpose of this experiment was to evaluate the host mouse response to wild-type Influenza A/Vietnam/1203/2004 (H5N1) virus, Influenza A/California/04/2009 (H1N1) virus, and Influenza A/Vietnam/1203/2004...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment ICL104 The purpose of this experiment was to evaluate the host response to Influenza A pandemic wild-type H1N1 (A/California/04/2009), natural isolate virus. Sample data was obtained from human lung adenocarcinoma...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment ICL103 The purpose of this experiment was to evaluate the human host response to Influenza A wild-type (H5N1) virus and mutant viruses. Sample data was obtained for human lung adenocarcinoma cell line ( Calu-3 )...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment ICL102 The purpose of this experiment was to evaluate the human host cellular response to wild-type Influenza A/Anhui/1/2013 (H7N9; "AH1-WT") virus and mutant viruses NS1-L103F/I106M ("AH1-F/M") and partially...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EU937001 The purpose of this experiment was to evaluate the human host response to Zaire Ebola wild-type virus and mutant virus infection. Samples were obtained from human histiocytic lymphoma cells (U937) , expressing...