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The pathogenesis of human Ebola virus disease (EVD) is complex. EVD is characterized by high levels of virus replication and dissemination, dysregulated immune responses, extensive virus- and host-mediated tissue damage, and disordered coagulation. To clarify how host responses contribute to EVD...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EH001 The purpose of this experiment was to evaluate the human patient peripheral blood mononuclear cells (PBMC) response to Zaire Ebola Makona virus infection during the 2013-2016 epidemic in West Africa. Samples were...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile Virus Experiment WLN002 The purpose of this experiment was to evaluate the host response to wild-type West Nile virus infectious clone (WNV-NY99 clone 382) and mutant (WNV-NY99 382 E218A 2 nt) virus infection. Sample data was...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile Virus Experiment WCT001 The purpose of this experiment was to evaluate the host response to wild-type West Nile Virus (WNV; WNV-NY99 382) and WNV-E218A (WNV-NY99 382 E218A 2 nt) mutant virus infection. Sample data was obtained from...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile Virus Experiment WCB001 The purpose of this experiment was to evaluate the host response to wild-type West Nile virus (WNV-NY99 382) and mutant WNV-E218A (WNV-NY99 382 E218A 2 nt) virus infection. Sample data was obtained from mouse...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment IM103 The purpose of this experiment was to evaluate the host response to wild-type Influenza A/Vietnam/1203/2004 (H5N1; "VN1203") virus infection and mock infection. Sample data was obtained for mouse lung tissue...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment IM102 The purpose of this experiment was to evaluate the mouse host response to wild-type Influenza A/Anhui/1/2013 (H7N9; "AH1-WT") virus and mutant viruses NS1-103F/106M ("AH1-F/M") and partially ferret-adapted (...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment IM101 The purpose of this experiment was to evaluate the host mouse response to wild-type Influenza A/Vietnam/1203/2004 (H5N1) virus, Influenza A/California/04/2009 (H1N1) virus, and Influenza A/Vietnam/1203/2004...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment ICL104 The purpose of this experiment was to evaluate the host response to Influenza A pandemic wild-type H1N1 (A/California/04/2009), natural isolate virus. Sample data was obtained from human lung adenocarcinoma...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment ICL103 The purpose of this experiment was to evaluate the human host response to Influenza A wild-type (H5N1) virus and mutant viruses. Sample data was obtained for human lung adenocarcinoma cell line (Calu-3)...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Influenza A Virus Experiment ICL102 The purpose of this experiment was to evaluate the human host cellular response to wild-type Influenza A/Anhui/1/2013 (H7N9; "AH1-WT") virus and mutant viruses NS1-L103F/I106M ("AH1-F/M") and partially...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EU937001 The purpose of this experiment was to evaluate the human host response to Zaire Ebola wild-type virus and mutant virus infection. Samples were obtained from human histiocytic lymphoma cells (U937), expressing...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EIHH002 This experiment evaluated Immortalized Human Hepatocyte (IHH) cell line host response to response to genetically-reconstructed Zaire Ebola virus infection. Processed Transcriptome Data Unavailable

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EIHH001 This experiment evaluated Immortalized Human Hepatocyte (IHH) cell line host response to wild-type Ebola viruses Zaire Ebola (ZEBOV '76) and Reston Ebola (REBOV '08) viral infection. Processed Transcriptome Data...

Integrative Omics

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EHUVEC001 The purpose of this experiment was to evaluate the human host response to Zaire Ebola wild-type virus and mutant virus infection in VP30 expression background. Sample data was obtained from human umbilical cord...

Integrative Omics