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Omics-LHV, West Nile Experiment WCN004 The purpose of this West Nile experiment was to obtain samples for omics analysis in mouse cerebral cortex neurons in response to wild-type West Nile Virus (WNV; WNV-NY99 382) and mutant WNV-E218A (WNV-NY99 382) viral infection. Overall Design: Mouse cortical...

Omics-LHV, West Nile Experiment WGCN004 The purpose of this West Nile experiment was to obtain samples for omics analysis in primary mouse granule neuron cells infected with wild type West Nile virus (WNV-NY99 clone 382, WNVWT) and mutant virus (WNVE218A). Overall Design: Granule cell neurons from...

pmartR Software Overview The pmartR package provides a single software tool for QC (filtering and normalization), exploratory data analysis (EDA), and statistical analysis (robust to missing data) and includes numerous visualization capabilities of mass spectrometry (MS) omics data (proteomic...

LIQUID Software Overview LIQUID provides users with the capability to process high throughput data and contains a customizable target library and scoring model per project needs. The graphical user interface provides visualization of multiple lines of spectral evidence for each lipid identification...

Model Soil Consortium 2 (MSC-2) Bacterial Isolate Genomes Model Soil Consortium 2 (MSC-2) bacterial isolate genome collections are derived from the soil consortium "MSC-1" multi-species cultured isolate genome collections from a previously reported WA-IsoC_MSC1.1.0 collection of a naturally evolved...

16s data from MSC-2 growth 3 fastq of 16s amplicon data of MSC2 1 csv file of raw ASV abundances for MSC2

Metatranscriptomic data from MSC-2 12 fastq files (6 forward read, 6 reverse read) describing transcriptomic response of MSC-2 during chitin growth. 1 csv file showing normalized gene expression values

PerCon SFA Project Publication Linked Data Catalog (uploads pending) The Persistence Control of Engineered Functions in Complex Soil Microbiomes Project (PerCon SFA), at Pacific Northwest National Laboratory (PNNL) is a Genomic Sciences Program, Biosystems Design, Research Science Focus Area project...

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"Visualizing the Hidden Half: Plant-Microbe Interactions in the Rhizosphere" Plant roots and the associated rhizosphere constitute a dynamic environment that fosters numerous intra- and interkingdom interactions, including metabolite exchange between plants and soil mediated by root exudates and the...

Pending Review Microbiomes contribute to multiple ecosystem services by transforming organic matter in soil. Extreme shifts in the environment, such as drying-rewetting cycles during drought, can impact microbial metabolism of organic matter by altering their physiology and function. These...

Multi-Omics Extended Data Package DOI Rapid Remodeling of the Soil Lipidome in Response to a Drying-Rewetting Event This study reveals specific changes in lipids and metabolites that are indicative of stress adaptation, substrate use, and cellular recovery during soil drying and subsequent rewetting...

ProxyTSPRD profiles are collected using NVIDIA Nsight Systems version 2020.3.2.6-87e152c and capture computational patterns from training deep learning-based time-series proxy-applications on four different levels: models (Long short-term Memory and Convolutional Neural Network), DL frameworks...

MPLEx Method Protocol for Integrative Single-Sample Processing for Subsequent Proteomic, Metabolomic, and Lipidomic Analyses The Metabolite, Protein and Lipid Extraction (MPLEx) method protocol is a robust sample processing technique applicable to a breadth of diverse sample types, including various...

"DNA Viral Diversity, Abundance, and Functional Potential Vary across Grassland Soils with a Range of Historical Moisture Regimes" Soil viruses are abundant, but the influence of the environment and climate on soil viruses remains poorly understood. Here, we addressed this gap by comparing the...

"Deconstructing the Soil Microbiome into Reduced-Complexity Functional Modules" The soil microbiome represents one of the most complex microbial communities on the planet, encompassing thousands of taxa and metabolic pathways, rendering holistic analyses computationally intensive and difficult. Here...