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To enable a comprehensive survey of the metabolic potential of complex soil microbiomes, we performed ultra-deep metagenome sequencing, collecting >1 terabase of sequence data from grassland soils representing different precipitation regimes. Soil samples representing a frequent precipitation regime...
As part of the Pacific Northwest National Laboratory’s (PNNL) Science Focus Area program, we are investigating the impact of environmental change on microbial community function in grassland soils. Three grassland soils, representing different moisture regimes, were selected for ultra-deep...

To enable a comprehensive survey of the metabolic potential of complex soil microbiomes, we performed ultra-deep metagenome sequencing, collecting >1 terabase of sequence data from grassland soils representing different precipitation regimes. Soil sample collections representing an arid regime soil...

Soil microorganisms play fundamental roles in cycling of soil carbon, nitrogen, and other nutrients, yet we have a poor understanding of how soil microbiomes are shaped by their nutritional and physical environment. In this study, we investigated the successional dynamics of a soil microbiome during...
Interactive data plots for proteomics and phosphoproteomics data from tumor (n=83) and normal tissue from high-grade serous ovarian cancer.

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Clinical Proteomic Tumor Analysis Consortium (CPTAC) ovarian cancer proteogenomics project. Characterization of tumors using proteomics and phosphoproteomics to identify signatures of drug resistance and characterize pathways associated with tumor versus normal tissue.

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  1. Datasets

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Omics-LHV, West Nile Experiment WLN002 The purpose of this West Nile experiment was to obtain serum samples for transcriptome analysis in mouse popliteal draining lymph nodes (DLN) infected with wild-type West Nile virus (WNV; WNV-NY99 382), and mutant WNV-E218A (WNV-NY99 382 E218A 2 nt). Overall...

Omics-LHV, West Nile Experiment WCT001 The purpose of this West Nile experiment was to obtain samples for omics analysis in mouse cortex tissue infected with wild-type West Nile Virus (WNV; WNV-NY99 382), and mutant WNV-E218A (WNV-NY99 382 E218A 2 nt). Overall Design: Mice were inoculated with WNV...

Omics-LHV, West Nile Experiment WCB001 The purpose of this West Nile experiment was to obtain samples for omics analysis in mouse cerebellum tissue infected with wild-type West Nile Virus (WNV; WNV-NY99 382), and mutant WNV-E218A (WNV-NY99 382 E218A 2 nt). Overall Design: Mice were inoculated with...

Influenza A Experiment IM103 The purpose of this experiment was to evaluate the human host response to wild-type Influenza A/Vietnam/1203/2004 (H5N1; VN1203) virus infection and mock infection. Sample data was obtained for mouse lung tissue for mRNA, miRNA, proteomics, lipidomics, and metabolomics...

Influenza A Experiment IM102 The purpose of this Influenza experiment was to obtain samples for mRNA, miRNA, proteomics, lipidomics, and metabolomics analysis in mouse lung infected with WT A/Anhui/1/2013 (H7N9; 'AH1'), AH - NS1-103F/106M, and AH1 - 691 (ferret adapted virus). Overall Design: Groups...

Influenza A Experiment IM101 The purpose of this experiment was to evaluate the Mus musculus host response to Influenza A wild-type (A/Vietnam/1203/2004; H5N1 | A/California/04/2009; H1N1) virus and H5N1 mutant virus (PB2-627E, NS1trunc124) infection. Sample data was obtained for mouse lung...

Influenza A Experiment ICL104 The purpose of this experiment was to evaluate the host response to Influenza A pandemic wild-type H1N1 (A/California/04/2009), natural isolate virus. Sample data was obtained for human Calu-3 cells infected with wild-type H1N1 virus (A/California/04/2009) for mRNA...

Influenza A Experiment ICL103 The purpose of this experiment was to evaluate the human host response to Influenza A wild-type (H5N1) virus and mutant viruses. Sample data was obtained for human lung adenocarcinoma cell line (Calu-3) infected with WT Influenza A/Vietnam/1203/2004 (H5N1, VN1203) and...

Influenza A Experiment ICL102 The purpose of this experiment was to evaluate the human host cellular response to wild-type Influenza A/Anhui/1/2013 (H7N9; "AH1-WT") virus and NS1-L103F/I106M ("AH1-F/M") and partially ferret-adapted ("AH1-691") mutant virus infection. Sample data was obtained from...