The severe acute respiratory syndrome coronavirus accessory protein ORF6 antagonizes interferon signaling by blocking karyopherin-mediated nuclear import processes. Viral nuclear import antagonists, expressed by several highly pathogenic RNA viruses, likely mediate pleiotropic effects on host gene...
Filter results
Tags
- (-) Health (23)
- (-) Mass Spectrometry (14)
- Virology (79)
- Immune Response (53)
- Time Sampled Measurement Datasets (50)
- Gene expression profile data (47)
- Differential Expression Analysis (46)
- Homo sapiens (34)
- Mass spectrometry data (31)
- Multi-Omics (30)
- Viruses (26)
- Omics (25)
- Virus (23)
- Soil Microbiology (21)
- MERS-CoV (18)
- Mus musculus (18)
- Synthetic (14)
- sequencing (13)
- West Nile virus (13)
- Genomics (12)
- Ebola (11)
- Influenza A (11)
- PerCon SFA (10)
- High Throughput Sequencing (9)
- Metagenomics (9)
- Resource Metadata (9)
- Microbiome (8)
- Proteomics (8)
- Machine Learning (7)
- Microarray (7)
Showing 31 - 37 of 37
Publication
The Systems Biology for Infectious Diseases Research program was established by the U.S. National Institute of Allergy and Infectious Diseases to investigate host-pathogen interactions at a systems level. This program generated 47 transcriptomic and proteomic datasets from 30 studies that...
Category
Respiratory infections stemming from influenza viruses and the Severe Acute Respiratory Syndrome corona virus (SARS-CoV) represent a serious public health threat as emerging pandemics. Despite efforts to identify the critical interactions of these viruses with host machinery, the key regulatory...
Category
Systems Virology Lethal Human Virus, SARS-CoV Experiment SHAE004 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome analysis in Human Airway Epithelial (HAE) cells infected with SARS-CoV, SARS deltaORF6, SARS BatSRBD mutants in a longitudinal study...
Category
Publication
Both highly pathogenic avian influenza virus and Middle East respiratory syndrome coronavirus (MERS-CoV) infections are characterized by severe disease and high mortality. The continued threat of their emergence from zoonotic populations underscores an important need to understand the dynamics of...
Category
The pathogenesis of human Ebola virus disease (EVD) is complex. EVD is characterized by high levels of virus replication and dissemination, dysregulated immune responses, extensive virus- and host-mediated tissue damage, and disordered coagulation. To clarify how host responses contribute to EVD...
Category
Project
The Phenotypic Response of the Soil Microbiome to Environmental Perturbations Project (Soil Microbiome SFA) at Pacific Northwest National Laboratory is a Genomic Sciences Program Science Focus Area (SFA) Project operating under the Environmental Microbiome Science Research Area. The Soil Microbiome...
Datasets
23