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Omics-LHV, MERS Experiment MFB001 The purpose of this MERS experiment was to obtain samples for omics analysis in primary human fibroblast response infected with wild-type MERS-CoV (icMERS-CoV). Overall Design: Human primary fibroblasts were infected in a multiplicity of 5 PFU per cell. Infected...

MERS-CoV Experiment MDC001 Processed Omics Data Unavailable This experiment evaluated primary human dendritic cells infected with a wild type MERS-CoV (icMERS) virus. Related Experimental Data BioProject: PRJNA315103 GEO: GSE79172 (mRNA transcriptome response) Acknowledgment of Federal Funding The...

Omics-LHV, MERS Experiment MCL002 The purpose of this MERS experiment was to obtain samples for omics analysis of Calu-3 cell response treated with wild-type MERS-CoV, MERS-CoV mutants and mockulum. Overall Design: 5 replicates at 6 time points (0, 3, 7, 12, 18 and 24 hr.) of 6 conditions (mock...

MERS-CoV Experiment MCL001 The purpose of this experiment was to evaluate the human host cellular response to wild-type Middle Eastern Respiratory Syndrome coronavirus (icMERS) and icMERS-CoV mutants icMERS-CoV-RFP, icMERS-CoV-dNSP16, icMERS-CoV-d4B, and icMERS-CoV-d3 virus infection. Sample time...

Interferon Experiment IFNaHUH001 The purpose of this experiment was to evaluate the human host cellular response to treatment with and without interferon alpha beta (IFNαβ) treatment. Sample time course data was obtained from human hepatoma carcinoma cells (HUH-7) expressing transcriptional...

Interferon Experiment IFNMVE001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to human interferon alpha beta (IFNαβ) or gamma (INFγ) treatment. Sample data was obtained from human primary lung microvascular endothelial (MVE) cells treated with or...

Interferon Experiment IFNFB001 The purpose of this experiment was to evaluate the human host cellular response to interferon alpha beta (IFNαβ) or interferon gamma (IFNγ) treatment. Sample data was obtained from primary human lung fibroblast (FB) cells inoculated with IFNαβ or IFNγ for transcriptome...

Interferon Experiment FNαCL001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to human interferon alpha (IFNα) treatment. Sample data was obtained from human immortalized human hepatocyte cells (IHH) treated with or without IFNα for mRNA and miRNA...

Interferon Experiment FNαCL001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to human interferon alpha (IFNα) treatment. Sample data was obtained from human lung adenocarcinoma cells (Calu-3) treated with or without IFNα for mRNA and miRNA...

Omics-LHV Profiling of Host Response to West Nile Virus Infection Background: West Nile virus (WNV) is classified as a Category B priority pathogen, by the National Institute of Allergy and Infectious Diseases (NIAID), and are known to cause severe and even fatal infections in humans where lethal...

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Omics-LHV Profiling of Host Response to Ebola Virus Infection Background Ebola virus (EBOV) is high risk biological agent classified as a Category A priority pathogen by the National Institute of Allergy and Infectious Diseases (NIAID) and is known to cause severe respiratory disease or hemorrhagic...

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Omics-LHV Profiling of Host Response to MERS-CoV Virus Infection Background: Middle East Respiratory Syndrome coronavirus (MERS-CoV) is classified as a Category C priority pathogen, by the National Institute of Allergy and Infectious Diseases (NIAID), and are known to cause severe and even fatal...

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Omics-LHV Profiling of Host Interferon-Stimulated Response to Virus Infection Data Reuse & Impact: Omics-LHV PNNL sub-projects provide a never before released comprehensive human interferon response collection of primary and secondary transformation multi-Omics data profiling a series of priority...

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The Phenotypic Response of the Soil Microbiome to Environmental Perturbations Project (Soil Microbiome SFA) at Pacific Northwest National Laboratory is a Genomic Sciences Program Science Focus Area (SFA) Project operating under the Environmental Microbiome Science Research Area. The Soil Microbiome...

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