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The Thermo Scientific (https://www.thermofisher.com/) "Velos Pro Orbitrap Mass Spectrometer" [MS:1003096] instrument data source combines advanced mass accuracy with an ultra-high resolution Orbitrap mass analyzer for increased sensitivity, enabling molecular weight determination for intact proteins...

The Thermo Scientific™ Q Exactive™ Plus Mass Spectrometer benchtop LC-MS/MS system [MS:1000494] combines quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection to deliver exceptional performance and versatility. Quadrupole technology optimizes precursor...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson MPLEx Method Protocol for Integrative Single-Sample Processing for Subsequent Proteomic, Metabolomic, and Lipidomic Analyses The Metabolite, Protein and Lipid Extraction (MPLEx) method protocol is a robust sample processing technique...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background Influenza A virus (IAV) is a high risk biological agent, classified as a Category C priority pathogen (Orthomyxoviridae) by the National Institute of Allergy and...

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Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile virus Experiment WSE001 The purpose of this experiment was to evaluate the mouse (C57BL6/JAX) mock-treated ("Koolaid") and/or drug treated (3Abx; Ampicillin, Vancomycin, and Neomycin) host response to wild-type West Nile virus (WNV...

MERS-CoV Experiment MCL003 The purpose of this experiment was to evaluate the human host response to wild-type icMERS-CoV virus infection and mockulum. Sample data was obtained from human lung adenocarcinoma cells (Calu-3) for proteome, metabolome, and lipidome expression analysis. Resulting...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Reusable Digital Data Lifecycle Downloads for Modeling Host Responses to Understand Severe Human Virus Infections The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host Responses to Understand Severe Human Virus...

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Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Experiment EH001 The purpose of this experiment was to evaluate the human patient peripheral blood mononuclear cells (PBMC) response to Zaire Ebola Makona virus infection during the 2013-2016 epidemic in West Africa. Samples were...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile Virus Experiment WCT001 The purpose of this experiment was to evaluate the host response to wild-type West Nile Virus (WNV; WNV-NY99 382) and WNV-E218A (WNV-NY99 382 E218A 2 nt) mutant virus infection. Sample data was obtained from...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile Virus Experiment WCB001 The purpose of this experiment was to evaluate the host response to wild-type West Nile virus (WNV-NY99 382) and mutant WNV-E218A (WNV-NY99 382 E218A 2 nt) virus infection. Sample data was obtained from mouse...

Influenza A Experiment IM103 The purpose of this experiment was to evaluate the host response to wild-type Influenza A/Vietnam/1203/2004 (H5N1; "VN1203") virus infection and mock infection. Sample data was obtained for mouse lung tissue for mRNA, miRNA, proteomics, lipidomics, and metabolomics...

Influenza A virus Experiment IM102 The purpose of this experiment was to evaluate the mouse host response to wild-type Influenza A/Anhui/1/2013 (H7N9; "AH1-WT") virus and mutant viruses NS1-103F/106M ("AH1-F/M") and partially ferret-adapted ("AH1-691") infection. Sample data was obtained from mouse...

Influenza A Experiment ICL104 The purpose of this experiment was to evaluate the host response to Influenza A pandemic wild-type H1N1 (A/California/04/2009), natural isolate virus. Sample data was obtained from human lung adenocarcinoma cells (Calu-3) with wild-type H1N1 virus (A/California/04/2009)...

Influenza A Experiment ICL103 The purpose of this experiment was to evaluate the human host response to Influenza A wild-type (H5N1) virus and mutant viruses. Sample data was obtained for human lung adenocarcinoma cell line (Calu-3) infected with WT Influenza A/Vietnam/1203/2004 (H5N1, VN1203) and...

Influenza A virus Experiment ICL102 The purpose of this experiment was to evaluate the human host cellular response to wild-type Influenza A/Anhui/1/2013 (H7N9; "AH1-WT") virus and mutant viruses NS1-L103F/I106M ("AH1-F/M") and partially ferret-adapted ("AH1-691") infection. Sample data was obtained...