The Human Islet Research Network (HIRN) is a large consortia with many research projects focused on understanding how beta cells are lost in type 1 diabetics (T1D) with a goal of finding how to protect against or replace the loss of functional beta cells. The consortia has multiple branches of...

The influence of tidal inundation dynamics on below ground carbon pools is poorly understood across coastal terrestrial-aquatic interface (TAI) ecosystems. The dynamic environmental conditions of tidally-influenced landscapes, the chemically complex nature of carbon compounds, the diverse nature of...

The Phenotypic Response of the Soil Microbiome to Environmental Perturbations Project (Soil Microbiome SFA) at Pacific Northwest National Laboratory is a Genomic Sciences Program Science Focus Area (SFA) Project operating under the Environmental Microbiome Science Research Area. The Soil Microbiome...

Some of the most rapid environmental changes on the planet are experienced in high-latitude regions. These changes affect all Earth system components, including the ocean, atmosphere, cryosphere, and marine and terrestrial ecosystems, and have both regional and global implications. The main...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Interferon-Stimulated Response to Virus Infection Background The human host Interferon ( IFN ) alpha, beta, and gamma participate in the body's natural immune response to lethal virus infection and disease. The...

Neisseria gonorrhoeae is a Gram-negative diplococcus that is responsible for the sexually transmitted infection gonorrhea, a high morbidity disease in the United States and worldwide. Over the last several years N. gonorrhoeae strains resistant to antibiotics used to treat this infection have begun...

The long-term goals of this scientific focus area (SFA) are to develop flexible and extensible modeling capabilities that capture the dynamic multiscale interactions among climate, energy, water, land, socioeconomics, critical infrastructure, and other sectors and to use these capabilities to study...

This project is an interdisciplinary collaboration supported by US DOE Office of Science's Scientific Discovery through Advanced Computing (SciDAC) program. The project addresses a crucial but largely overlooked source of error in the Energy Exascale Earth System Model (E3SM) and other atmosphere...

The PNNL-SERDP database was constructed by PNNL to generate the quantitative infrared spectra of gases associated with biomass burning; the reference data are to allow detection and quantification of such gases via infrared absorption spectroscopy. Candidates for the database were selected based on...

The Predicting Ecosystem Resilience through Multiscale Integrative Science (PREMIS) database was generated to mechanistically understand how feedbacks across scales, from molecular to plant to plant populations and communities to ecosystems, govern the resilience of system functions to elevated CO2...

The EyeSea underwater video dataset was assembled for developing algorithms for detecting fish in real world underwater video data. The data were recorded as part of environmental monitoring efforts at three different water power sites.

The objective of Terrestrial-Aquatic Interface (TAI) research in PREMIS is to understand the factors governing C and nutrient movement and transformation through the TAI, and their sensitivities to inundation and salinity within coastal watersheds.

Accurate characterization of the global downward shortwave (SW) and photosynthetically active radiation (PAR) is fundamental for Earth system modeling and global change research. Combined with a machine-learning method, we used the Earth Polychromatic Imaging Camera (EPIC) data onboard the Deep...

Last updated on 2023-02-23T19:37:46+00:00 by LN Anderson PerCon SFA Project Publication Experimental Data Catalog The Persistence Control of Engineered Functions in Complex Soil Microbiomes Project (PerCon SFA) at Pacific Northwest National Laboratory ( PNNL ) is a Genomic Sciences Program...

The Environmental Determinants of Diabetes in the Young (TEDDY) study is searching for factors influencing the development of type 1 diabetes (T1D) in children. Research has shown that there are certain genes that correlate to higher risk of developing T1D, but not all children with these genes...