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Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EIHH001 This experiment evaluated Immortalized Human Hepatocyte ( IHH ) cell line host response to wild-type Ebola viruses Zaire Ebola (ZEBOV '76) and Reston Ebola (REBOV '08) viral infection. Processed Transcriptome...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EIHH002 This experiment evaluated Immortalized Human Hepatocyte ( IHH ) cell line host response to response to genetically-reconstructed Zaire Ebola virus infection. Processed Transcriptome Data Unavailable

Soil microorganisms play fundamental roles in cycling of soil carbon, nitrogen, and other nutrients, yet we have a poor understanding of how soil microbiomes are shaped by their nutritional and physical environment. In this study, we investigated the successional dynamics of a soil microbiome during...
As part of the Pacific Northwest National Laboratory’s (PNNL) Science Focus Area program, we are investigating the impact of environmental change on microbial community function in grassland soils. Three grassland soils, representing different moisture regimes, were selected for ultra-deep...
The soil microbiome is central to the cycling of carbon and other nutrients and to the promotion of plant growth. Despite its importance, analysis of the soil microbiome is difficult due to its sheer complexity, with thousands of interacting species. Here, we reduced this complexity by developing...

"Deconstructing the Soil Microbiome into Reduced-Complexity Functional Modules" The soil microbiome represents one of the most complex microbial communities on the planet, encompassing thousands of taxa and metabolic pathways, rendering holistic analyses computationally intensive and difficult. Here...

"Visualizing the Hidden Half: Plant-Microbe Interactions in the Rhizosphere" Plant roots and the associated rhizosphere constitute a dynamic environment that fosters numerous intra- and interkingdom interactions, including metabolite exchange between plants and soil mediated by root exudates and the...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Ebola Virus Infection Background Ebola virus ( EBOV ) is a high risk biological agent, belonging to the Flaviviridae family, and is classified as a Category A priority pathogen by the National Institute...

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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...

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Last updated on 2023-02-23T19:37:46+00:00 by LN Anderson PerCon SFA Project Publication Experimental Data Catalog The Persistence Control of Engineered Functions in Complex Soil Microbiomes Project (PerCon SFA) at Pacific Northwest National Laboratory ( PNNL ) is a Genomic Sciences Program...

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Bruker Daltonics SolariX Magnetic Resonance Mass Spectrometry (MRMS) instruments are available for different magnetic field strengths of 7T, 12T and 15T. The SolariX XR and 2xR instruments use magnetron control technology and a newly developed, high sensitivity, low noise preamplifier to exploit...

Stanford Synchrotron Radiation Lightsource Experimental Station 14-3b is a bending magnet side station dedicated to X-Ray Imaging and Micro X-Ray Absorption Spectroscopy of biological, biomedical, materials, and geological samples. Station 14-3b is equipped with specialized instrumentation for XRF...

The innovative Elstar™ electron column forms the basis of the Helios NanoLab’s outstanding high resolution imaging performance. The Elstar features unique technologies, such as constant power lenses for higher thermal stability, electrostatic scanning for faster, higher accurate imaging, and unique...

The Nikon Eclipse Ti2-E is a motorized and intelligent model for advanced imaging applications. Compatible with PFS, auto correction collar, and external phase contrast system. The base of choice for live-cell imaging, high-content applications, confocal and super-resolution.As research trends...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaHUH001 The purpose of this experiment was to evaluate the human host cellular response to treatment with and without interferon alpha/beta (IFNα/β) treatment. Sample time course data was obtained from human hepatoma...