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Biography Carrie Nicora is a senior research scientist (chemist III) at PNNL, specializing in high-throughput scientific research sample management using modular automation techniques for processing a wide range of biological specimens for proteomic, metabolomic, and lipidomic analysis. She is an...

Biography Kristin Burnum-Johnson is a senior scientist and team lead of the Biomolecular Pathways team at PNNL. Burnum-Johnson earned her PhD in Biochemistry from Vanderbilt University with Professor Richard M. Caprioli and then completed a postdoctoral fellowship at PNNL with Dr. Richard D. Smith...

"Deconstructing the Soil Microbiome into Reduced-Complexity Functional Modules" The soil microbiome represents one of the most complex microbial communities on the planet, encompassing thousands of taxa and metabolic pathways, rendering holistic analyses computationally intensive and difficult. Here...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background Influenza A virus ( IAV ) is a high risk biological agent belonging to the Orthomyxoviridae family is classified as a Category C priority pathogen by the National...

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Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile Virus Experiment WSE001 The purpose of this experiment was to evaluate the host response to wild-type West Nile (WNV-NY99 382) virus infection. Sample data was obtained from mouse (C57BL6/JAX) serum from mock-treated "Koolaid" and...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile Virus Experiment WLN003 The purpose of this experiment was to evaluate the host response to wild-type West Nile virus infectious clone (WNV-NY99 clone 382) and mutant WNV-E218A (WNV-NY99 382 E218A 2 nt) virus infection. Sample data...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson West Nile Virus Experiment WDC010 The purpose of this experiment was to evaluate the host response to wild-type West Nile virus (WNVMT) and mutant (WNVE218A) virus infection. Sample data was obtained from primary mouse myeloid dendritic cells...

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson MERS-CoV Experiment MCL003 The purpose of this experiment was to evaluate the human host response to wild-type infectious clone of Middle Eastern Respiratory Syndrome coronavirus (icMERS-CoV) infection and mockulum. Sample data was obtained...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases ( NIAID ) "Modeling Host...

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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EH001 The purpose of this experiment was to evaluate the human patient peripheral blood mononuclear cells (PBMC) response to Zaire Ebola Makona virus infection during the 2013-2016 epidemic in West Africa. Samples were...

Please cite as : Anderson L.N., J.E. McDermott, and R.S. McClure. 2020. WA-IsoC_MSC1.1.0 (Amplicon 16S rRNA, WA). [Data Set] PNNL DataHub. https://doi.org/10.25584/WAIsoCMSC1/1635272 The soil microbiome is central to the cycling of carbon and other nutrients and to the promotion of plant growth...

The soil microbiome is central to the cycling of carbon and other nutrients and to the promotion of plant growth. Despite its importance, analysis of the soil microbiome is difficult due to its sheer complexity, with thousands of interacting species. Here, we reduced this complexity by developing...
Please cite as : Anderson L.N., W.C. Nelson, J.E. McDermott, R. Wu, S.J. Fansler, Y. Farris, and J.K. Jansson, et al. 2020. KS-TmG.1.0 (Metagenome, KS). [Data Set] PNNL DataHub. https://doi.org/10.25584/KSTmG1/1635004 To enable a comprehensive survey of the metabolic potential of complex soil...
Please cite as : Anderson L.N., W.C. Nelson, J.E. McDermott, R. Wu, S.J. Fansler, Y. Farris, and J.K. Jansson, et al. 2020. IA-TmG.1.0 (Metagenome, IA). [Data Set] PNNL DataHub. https://doi.org/10.25584/IATmG1/1635005 To enable a comprehensive survey of the metabolic potential of complex soil...
As part of the Pacific Northwest National Laboratory’s (PNNL) Science Focus Area program, we are investigating the impact of environmental change on microbial community function in grassland soils. Three grassland soils, representing different moisture regimes, were selected for ultra-deep...