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Dataset
Omics-Lethal Human Viruses, Ebola Experiment EIHH001

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EIHH001 This experiment evaluated Immortalized Human Hepatocyte ( IHH ) cell line host response to wild-type Ebola viruses Zaire Ebola (ZEBOV '76) and Reston Ebola (REBOV '08) viral infection. Processed Transcriptome...

Biology
Human Health
Integrative Omics
Dataset
Omics-Lethal Human Viruses, Ebola Experiment EIHH002

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EIHH002 This experiment evaluated Immortalized Human Hepatocyte ( IHH ) cell line host response to response to genetically-reconstructed Zaire Ebola virus infection. Processed Transcriptome Data Unavailable

Biology
Human Health
Integrative Omics
Publication
Selection, Succession, and Stabilization of Soil Microbial Consortia
Soil microorganisms play fundamental roles in cycling of soil carbon, nitrogen, and other nutrients, yet we have a poor understanding of how soil microbiomes are shaped by their nutritional and physical environment. In this study, we investigated the successional dynamics of a soil microbiome during...
Earth System Science
Biology
Publication
Draft Genome of Fusarium sp. strain DS 682, a novel Fungal isolate from the Grass Rhizosphere
The novel fungal strain, Fusarium sp. DS 682, was isolated from the rhizosphere of the perennial grass, Bouteloua gracilis , at the Konza Prairie Biological Station in Kansas. This fungal strain is common across North American grasslands and is resilient to environmental fluctuations. The draft...
Earth System Science
Biology
Dataset
Omics-Lethal Human Viruses, MERS-CoV Experiment MDC001

MERS-CoV Experiment MDC001 Processed Omics Data Unavailable This experiment evaluated primary human dendritic cells infected with a wild type MERS-CoV (icMERS) virus. Related Experimental Data BioProject: PRJNA315103 GEO: GSE79172 (mRNA transcriptome response) Acknowledgment of Federal Funding The...

Biology
Human Health
Integrative Omics
Publication
Terabase Metagenome Sequencing of Grassland Soil Microbiomes
As part of the Pacific Northwest National Laboratory’s (PNNL) Science Focus Area program, we are investigating the impact of environmental change on microbial community function in grassland soils. Three grassland soils, representing different moisture regimes, were selected for ultra-deep...
Earth System Science
Biology
Publication
Development and Analysis of a Stable, Reduced Complexity Model Soil Microbiome
The soil microbiome is central to the cycling of carbon and other nutrients and to the promotion of plant growth. Despite its importance, analysis of the soil microbiome is difficult due to its sheer complexity, with thousands of interacting species. Here, we reduced this complexity by developing...
Biology
Earth System Science
Dataset
Omics-Lethal Human Viruses, Influenza A Experiment IM104

Influenza A Experiment IM104 Processed Omics Data Unavailable This Influenza experiment evaluated mouse lung expression after etoposide treatment and infection with a pandemic H1N1 influenza strain. Related Experimental Data BioProject: PRJNA382278 GEO: GSE97555 (mRNA transcriptome response)...

Biology
Human Health
Integrative Omics
Publication
Fungal Mineral Weathering Mechanisms Revealed Through Direct Molecular Visualization (preprint)

Soil fungi facilitate the translocation of inorganic nutrients from soil minerals to other microorganisms and plants. This ability is particularly advantageous in impoverished soils, because fungal mycelial networks can bridge otherwise spatially disconnected and inaccessible nutrient hotspots...

Biology
Earth System Science
Publication
DNA Viral Diversity, Abundance, and Functional Potential Vary across Grassland Soils with a Range of Historical Moisture Regimes

"DNA Viral Diversity, Abundance, and Functional Potential Vary across Grassland Soils with a Range of Historical Moisture Regimes" Soil viruses are abundant, but the influence of the environment and climate on soil viruses remains poorly understood. Here, we addressed this gap by comparing the...

Biology
Earth System Science
Publication
Deconstructing the Soil Microbiome into Reduced-Complexity Functional Modules

"Deconstructing the Soil Microbiome into Reduced-Complexity Functional Modules" The soil microbiome represents one of the most complex microbial communities on the planet, encompassing thousands of taxa and metabolic pathways, rendering holistic analyses computationally intensive and difficult. Here...

Biology
Earth System Science
Publication
Rapid remodeling of the soil lipidome in response to a drying-rewetting event

Pending Review Microbiomes contribute to multiple ecosystem services by transforming organic matter in soil. Extreme shifts in the environment, such as drying-rewetting cycles during drought, can impact microbial metabolism of organic matter by altering their physiology and function. These...

Biology
Microbiome Science
Earth System Science
Resource
R Source Code for Fusarium DS 682 Fungal Isolate Proteogenomics Statistical Analysis

Fusarium sp. DS682 Proteogenomics Statistical Data Analysis of SFA dataset download: 10.25584/KSOmicsFspDS682/1766303 . GitHub Repository Source: https://github.com/lmbramer/Fusarium-sp.-DS-682-Proteogenomics MaxQuant Export Files (txt) Trelliscope Boxplots (jsonp) Fusarium Report (.Rmd, html)...

Microbiome Science
Computational Mathematics & Statistics
Method
MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses

Last updated on 2024-03-21T18:47:20+00:00 by LN Anderson MPLEx Method Protocol for Integrative Single-Sample Processing for Subsequent Proteomic, Metabolomic, and Lipidomic Analyses Method Source Contributions LN Anderson , Data Curation The Metabolite, Protein and Lipid Extraction (MPLEx) method...

Scientific Discovery
Integrative Omics
Biology
Dataset
WA-TmG.1.0 (Metagenome, WA)

Please cite as : Anderson L.N., W.C. Nelson, J.E. McDermott, R. Wu, S.J. Fansler, Y. Farris, and J.K. Jansson, et al. 2020. WA-TmG.1.0 (Metagenome, WA). [Data Set] PNNL DataHub. https://doi.org/10.25584/WATmG1/1635002 To enable a comprehensive survey of the metabolic potential of complex soil...

Biology
Earth System Science