The severe acute respiratory syndrome coronavirus accessory protein ORF6 antagonizes interferon signaling by blocking karyopherin-mediated nuclear import processes. Viral nuclear import antagonists, expressed by several highly pathogenic RNA viruses, likely mediate pleiotropic effects on host gene...
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The Systems Biology for Infectious Diseases Research program was established by the U.S. National Institute of Allergy and Infectious Diseases to investigate host-pathogen interactions at a systems level. This program generated 47 transcriptomic and proteomic datasets from 30 studies that...
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Respiratory infections stemming from influenza viruses and the Severe Acute Respiratory Syndrome corona virus (SARS-CoV) represent a serious public health threat as emerging pandemics. Despite efforts to identify the critical interactions of these viruses with host machinery, the key regulatory...
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The Community Land Model (CLM) is an effective tool to simulate the biophysical and biogeochemical processes and their interactions with the atmosphere. Although CLM Version 5 (CLM5) constitutes various updates in these processes, its performance in simulating energy, water and carbon cycles over...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...
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Both highly pathogenic avian influenza virus and Middle East respiratory syndrome coronavirus (MERS-CoV) infections are characterized by severe disease and high mortality. The continued threat of their emergence from zoonotic populations underscores an important need to understand the dynamics of...
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The pathogenesis of human Ebola virus disease (EVD) is complex. EVD is characterized by high levels of virus replication and dissemination, dysregulated immune responses, extensive virus- and host-mediated tissue damage, and disordered coagulation. To clarify how host responses contribute to EVD...
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Dr. Katrina Waters is the division director for Biological Sciences at the Pacific Northwest National Laboratory. Waters has a Ph.D. in biochemistry and more than 15 years of experience in microarray and proteomics data analysis. Her research interests are focused on the integration of genomics...
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Washington State University Distinguished Graduate Research Program Program: Chemical Engineering WSU-PNNL Advisor: Aaron Wright
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Earth Scientist Emily Graham is an quantitative ecosystem ecologist in the Biological Sciences Group at PNNL and is part of the Ecosystem Science Team. She is co-principal investigator of the Subsurface Biogeochemical Research Science Focus Area (SFA) and a key member of PNNL’s soil microbiome SFA...
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Dr. Bernstein is an Associate Professor in UiT's Arctic Centre for Sustainable Energy (ARC). He specializes in genome-enabled bioengineering with microbes and microbial communities. His research is at the juxtaposition of biotechnology and microbial ecology as applied to the fields of sustainable...
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Colin works in microbial ecology, focusing on informatics and visualization. Education: BS - Biology and Informatics - Juniata College
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The novel fungal strain, Fusarium sp. DS 682, was isolated from the rhizosphere of the perennial grass, Bouteloua gracilis , at the Konza Prairie Biological Station in Kansas. This fungal strain is common across North American grasslands and is resilient to environmental fluctuations. The draft...
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Coastal landscapes are increasingly exposed to seawater due to sea level rise and extreme weather events. The biogeochemical responses of these vulnerable ecosystems are poorly understood, limiting our ability to predict how their role in global biogeochemical cycles will shift under future...
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Education: University of California-Berkeley, PhD Plant Biology University of California-Davis, BS Plant Biology Publications: 2020 Naylor D.T., S.J. Fansler, C.J. Brislawn, W.C. Nelson, K.S. Hofmockel, J.K. Jansson, and R.S. McClure. 2020. "Deconstructing the Soil Microbiome into Reduced-Complexity...
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