Omics Lethal Human Virus, SARS-CoV Experiment SM001
New uploads pending
The purpose of this experiment was to evaluate the human host response to Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) wild-type virus. Sample data was obtained for 20 week-old C57BL/6J mouse lung tissue infected with different intranasal instillation doses of SARS CoV MA15 for transcriptomics and proteomics experimental measurements. Infected samples were collected with 3 time-matched mocks in parallel and harvested across 4 different collection days post infection. Sample collection time points: 1, 2, 4 and 7 days post-infection (4-5 biological replicates, per time point, per dose).
SARS-CoV Experimental Species:
- Mouse-adapted SARS-CoV (MA15)
- Mus musculus (primary lung tissue)
Processed Omics Data (available at download button):
Dataset downloads contain one or more statistically processed data files related to a transcriptomic, proteomic, metabolomic, and/or lipidomic dataset collection associated with a Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) experimental study.
- Expression profiling by array (mRNA)
- Protein quantification by liquid chromatography mass spectrometry (LC-MS)
Related Experimental Data
This work is a contribution of the "Systems Biology for Infectious Diseases Research Program" Project (Contract HHSN272200800060C | NIH, NIAID)
GEO Accession: GSE33266 (transcriptome response)
Array Platform: GPL4134
PRIDE Accession: PXD015553 (proteome response)
PeptideAtlas Accession: PASS00433