Systems Virology Lethal Human Virus, SARS-CoV Experiment SM003
New uploads pending
The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in C57BlL/6 mice lung infected with dicSARS CoV, SARS MA15 wild type and SARS BatSRBD mutant virus.
Overall Design: Twenty-week-old C57BL/6 mice were infected icSARS CoV, Wild Type SARS MA15 or SARS BatSRBD mutant viruses at 10^4 or 10^5 PFU (mock-infected with PBS alone). Lungs were harvested and total RNA was isolated and subjected to microarray analysis (experimental design was for 3-5 mice/time point/dose and 3 time-matched mocks). Time points used were: 1, 2, 4 and 7 days post-infection.
Processed Omics Data (available at download button):
Dataset downloads contain one or more statistically processed data file related to a lipidomic, transcriptomic, metabolomic, and/or proteomic dataset collection associated with the SARS experimental study.
Related Experimental Data
GEO Dataset: GSE50000