Systems Virology Lethal Human Virus, SARS-CoV Experiment SM012
New uploads pending
The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in C57Bl/6 mice infected with SARS MA15 or SARS deltaORF6 mutant viruses.
Overall Design: Twenty-week-old C57BL/6 mice were infected with wild type SARS MA15 or SARS deltaORF6 mutant viruses at 10^5 PFU. Infected samples included time-matched mock collections in parallel. Lung samples were collected for virus load for 3 mice/time point/dose. Time points used were: 1, 2, 4 and 7 days post-infection.
Processed Omics Data (available at download button):
Dataset downloads contain one or more statistically processed data file related to a lipidomic, transcriptomic, metabolomic, and/or proteomic dataset collection associated with the SARS experimental study.
Related Experimental Data
GEO Dataset: GSE49262
Host Factor Experiment(s): SM012-R (ViPR, NIAID Systems Biology)