Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL012
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The purpose of this SARS experiment was to obtain samples for metabolome and lipidome analysis comparing wild type virus (icSARS) vs icSARS CoV deltaORF6 infected Human lung tissue 2B4 (Calu-3 clonal derivative) cells to mock infected cells.
Overall Design: Human lung tissue 2B4 cells (clonal derivatives of Calu-3 cells) were infected with CoVcSARS CoV and icSARS CoV deltaORF 6 mutant virus. Cells were mock-infected or infected with virus (n = 3 each) at an MOI of 5 and harvested at 0, 12, 24, 36, 48, 60, and 72 h post-infection. Lipids were analyzed with positive and negative ionization.
Processed Omics Data (available at download button):
Dataset downloads contain one or more statistically processed data file related to a lipidomic, transcriptomic, metabolomic, and/or proteomic dataset collection associated with the SARS experimental study.
Related Experimental Data