Publication - Journal Article Direct Involvement of Type II Secretion System in Extracellular Translocation of Shewanella oneidensis Outer Membrane Cytochromes MtrC and OmcA

Journal of Bacteriology, vol. 190, iss. 15, pp. 5512-5516, 2008

Liang Shi, Shuang Deng, Matthew J. Marshall, Zheming Wang, David W. Kennedy, Alice C. Dohnalkova, Heather M. Mottaz, Eric A. Hill, Yuri A. Gorby, Alexander S. Beliaev, David J. Richardson, John M. Zachara, James K. Fredrickson

ABSTRACT MtrC and OmcA are cell surface-exposed lipoproteins important for reducing solid metal oxides. Deletions of type II secretion system (T2SS) genes reduced their extracellular release and their accessibility to the proteinase K treatment, demonstrating the direct involvement of T2SS in translocation of MtrC and OmcA to the bacterial cell surface.