Publication - Journal Article The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

https://doi.org/10.1038/s41586-019-1629-x
Journal Article
Nature, vol. 574, iss. 7777, pp. 187-192, 2019
Authors
, Michael P. Snyder, Shin Lin, Amanda Posgai, Mark Atkinson, Aviv Regev, Jennifer Rood, Orit Rozenblatt-Rosen, Leslie Gaffney, Anna Hupalowska, Rahul Satija, Nils Gehlenborg, Jay Shendure, Julia Laskin, Pehr Harbury, Nicholas A. Nystrom, Jonathan C. Silverstein, Ziv Bar-Joseph, Kun Zhang, Katy Börner, Yiing Lin, Richard Conroy, Dena Procaccini, Ananda L. Roy, Ajay Pillai, Marishka Brown, Zorina S. Galis, Long Cai, Jay Shendure, Cole Trapnell, Shin Lin, Dana Jackson, Michael P. Snyder, Garry Nolan, William James Greenleaf, Yiing Lin, Sylvia Plevritis, Sara Ahadi, Stephanie A. Nevins, Hayan Lee, Christian Martijn Schuerch, Sarah Black, Vishal Gautham Venkataraaman, Ed Esplin, Aaron Horning, Amir Bahmani, Kun Zhang, Xin Sun, Sanjay Jain, James Hagood, Gloria Pryhuber, Peter Kharchenko, Mark Atkinson, Bernd Bodenmiller, Todd Brusko, Michael Clare-Salzler, Harry Nick, Kevin Otto, Amanda Posgai, Clive Wasserfall, Marda Jorgensen, Maigan Brusko, Sergio Maffioletti, Richard M. Caprioli, Jeffrey M. Spraggins, Danielle Gutierrez, Nathan Heath Patterson, Elizabeth K. Neumann, Raymond Harris, Mark deCaestecker, Agnes B. Fogo, Raf van de Plas, Ken Lau, Long Cai, Guo-Cheng Yuan, Qian Zhu, Ruben Dries, Peng Yin, Sinem K. Saka, Jocelyn Y. Kishi, Yu Wang, Isabel Goldaracena, Julia Laskin, DongHye Ye, Kristin E. Burnum-Johnson, Paul D. Piehowski, Charles Ansong, Ying Zhu, Pehr Harbury, Tushar Desai, Jay Mulye, Peter Chou, Monica Nagendran, Ziv Bar-Joseph, Sarah A. Teichmann, Benedict Paten, Robert F. Murphy, Jian Ma, Vladimir Yu. Kiselev, Carl Kingsford, Allyson Ricarte, Maria Keays, Sushma A. Akoju, Matthew Ruffalo, Nils Gehlenborg, Peter Kharchenko, Margaret Vella, Chuck McCallum, Katy Börner, Leonard E. Cross, Samuel H. Friedman, Randy Heiland, Bruce Herr, Paul Macklin, Ellen M. Quardokus, Lisel Record, James P. Sluka, Griffin M. Weber, Nicholas A. Nystrom, Jonathan C. Silverstein, Philip D. Blood, Alexander J. Ropelewski, William E. Shirey, Robin M. Scibek, Paula Mabee, W. Christopher Lenhardt, Kimberly Robasky, Stavros Michailidis, Rahul Satija, John Marioni, Aviv Regev, Andrew Butler, Tim Stuart, Eyal Fisher, Shila Ghazanfar, Jennifer Rood, Leslie Gaffney, Gokcen Eraslan, Tommaso Biancalani, Eeshit D. Vaishnav, Richard Conroy, Dena Procaccini, Ananda Roy, Ajay Pillai, Marishka Brown, Zorina Galis, Pothur Srinivas, Aaron Pawlyk, Salvatore Sechi, Elizabeth Wilder, James Anderson, , , , , , , , , , , , , , , , ,
Abstract
AbstractTransformative technologies are enabling the construction of three-dimensional maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) intends to develop a widely accessible framework for comprehensively mapping the human body at single-cell resolution by supporting technology development, data acquisition, and detailed spatial mapping. HuBMAP will integrate its efforts with other funding agencies, programs, consortia, and the biomedical research community at large towards the shared vision of a comprehensive, accessible three-dimensional molecular and cellular atlas of the human body, in health and under various disease conditions.
English