Quantification of microtubule stutters: dynamic instability behaviors that are strongly associated with catastrophe

Journal Article
Molecular Biology of the Cell, vol. 33, iss. 3, 2022
Authors
Shant M. Mahserejian, Jared P. Scripture, Ava J. Mauro, Elizabeth J. Lawrence, Erin M. Jonasson, Kristopher S. Murray, Jun Li, Melissa Gardner, Mark Alber, Marija Zanic, Holly V. Goodson, Claire Walczak
Abstract
STADIA analysis quantifies stutters and associated transitions in microtubule dynamics. Most catastrophes involve stutters, and the anticatastrophe factor CLASP2γ works by converting growth-stutter-shortening events (i.e., transitional catastrophes) to growth-stutter-growth events (i.e., interrupted growth).
English