Publication - Journal Article Ultrasensitive single-cell proteomics workflow identifies >1000 protein groups per mammalian cell

https://doi.org/10.1039/d0sc03636f
Journal Article
Chemical Science, vol. 12, iss. 3, pp. 1001-1006, 2021
Authors
Yongzheng Cong, Khatereh Motamedchaboki, Santosh A. Misal, Yiran Liang, Amanda J. Guise, Thy Truong, Romain Huguet, Edward D. Plowey, Ying Zhu, Daniel López-Ferrer, Ryan T. Kelly
Abstract
The combination of nanodroplet sample preparation, ultra-low-flow nanoLC, high-field asymmetric ion mobility spectrometry (FAIMS) and latest-generation mass spectrometry instrumentation provides dramatically improved single-cell proteome profiling.
English