The current dataset contains data upload links to the following hydrologic (water balance), river routing (water management), and hydropower simulation data over CONUS: Climate Forcing: Livneh ( https://www.nature.com/articles/sdata201542 ) Simulation Scenario: Historical Simulation Period: 1971...

The current dataset contains data upload links to the following hydrologic (water balance), river routing (water management), and hydropower simulation data over CONUS: Climate Forcing: ClimRR ( https://climrr.anl.gov/climrrdata ) Simulation Scenario: Historical, Mid-Century, End-Century Simulation...

Dataset Description This dataset is a Knowledge Graph (KG) projection is a graph of a subset of RB-Tnseq experimental data and associated biological and experimental metadata from the Fitness Browser. The KG is hosted as a Neo4j graph database, and contains three trained neural network models: A...

Wan H., C.D. Burleyson, and N. Voisin. 2025. "Heat wave and cold snap event library under various technical choices for NERC subregions in the conterminous U.S. (1980 - 2024)." PNNL-SA-217022. Citation will be updated once the associated manuscript is accepted. This Extreme Thermal Event Library...

This data package consists of data from MIN6 cells (n=4) treated with IL-1β + IFNγ + TNFα for 24 h post RNAi targeting 85/88 kDa calcium-independent phospholipase A2 ( Pla2g6 ) and submitted to proteomics analysis ( Table 1 ). Pla2g6 is an enzyme that metabolizes phosphatidylcholine (PCs) into...

This data package consists of data from MIN6 cells (n=4) treated with IL-1β + IFNγ + TNFα and RNAi targeting Poly(ADP)ribosyl polymerase 12 ( Parp12 ) for 24 h and submitted to proteomic analyses ( Table 1 ). PARP12 is an interferon-induced protein known to target viral RNA to stress granules. It...

This data package consists of data from β-TC-6 cells treated with IFNγ + IL-1β for 4, 8 or 24 h (n=4) and submitted to enrichment of cysteine-containing peptides (redox), phosphopeptides and acetylated peptides. This enabled the analysis of proteomics, redox cysteine, phosphoproteomics and...

This data package consists of data from human islets treated for 48 h with cytokines (IFNγ, TNFα, and/or IL1β), thapsigargin (TG), brefeldin A (BFA), or DMSO for the control (CTRL) and submitted for single-cell RNA-seq (n=5) and single-nucleus multi-omics sequencing (snMultiomics-seq, n=1) ( Table 1...

This data package consists of data from sets of β-TC-3 cells (n=3) treated with IL-1β + IFNγ + TNFα for 24 h with or without ML351 and submitted to RNA-seq ( Table 1 ). ML351 is an inhibitor of 12-lipoxygenase, an enzyme that produces 12-HETE. Therefore, this treatment was done to study whether...

This data package consists of data from paired human islets treated with IFNγ + IL-1β for 48 h and submitted to RNA-seq (n=5), ATAC-seq (n=5), UMI-4C18 (n=2 or 3, depending on the viewpoint), and ChIP-seq for histone H3 lysine 27 acetylation (H3K27Ac) (n=4) ( Table 1 ). Islets across the study...

This data package consists of data from human islets (n=6) treated with IFNγ + IL-1β for 24 h and submitted to top-down proteomics ( Table 1 ). Data contributors: Ashley Ives, Wei-Jun Qian & James Fulcher: Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, 99354, USA...

The data package consists of RNA-seq data from human islet-derived exosomes post IFNγ + IL-1β treatment of human islets (n=5) for 24 h ( Table 1 ). Data contributors: Preethi Krishnan& Carmella Evans-Molina: Department of Diabetes Immunology, Beckman Research Institute, City of Hope, Duarte, CA, USA...

This data package consists of data from MIN6 cells (n=4) treated with IL-1β + IFNγ + TNFα for 24 h post-RNAi targeting ADP-ribosylhydrolase ARH3 (Adprhl2), and submitted to proteomics analysis ( Table 1 ). ARH3 is a hydrolase that keeps cellular ADP-ribosylation levels in check and is regulated by...

This data package consists of data from human islets (n=5) treated with IFNγ + IL-1β with or without difluoromethylornithine (DFMO) and submitted to RNA-seq and proteomics analysis ( Table 1 ). DFMO is an inhibitor of ornithine decarboxylase (ODC), an enzyme of the polyamine pathway. Therefore, this...

The data package consists of data from iPSC: HEL115.6-derived islet-like aggregates treated with IFNα for 24 h and submitted to RNA-seq (n=5) and scRNA-seq (n=5). ( Table 1 ). Data contributors: Arturo Roca-Rivada, Xiaoyan Yi & Décio L. Eizirik: ULB Center for Diabetes Research, Medical Faculty...