Interferon Experiment IFNMVE001
The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to human interferon alpha beta (IFNαβ) or gamma (INFγ) treatment. Sample data was obtained from human primary lung microvascular endothelial (MVE) cells treated with or without human IFNαβ or INFγ for mRNA transcriptome expression analysis.
Accessible Multi-Omics Digital Data Downloads
Secondary host-associated viral dataset downloads contain one or more qualitative and/or quantitative statistically processed (normalization data transformation) expression analysis file(s) resulting from primary viral experimental study designs leveraging unique high-resolution Omics capabilities. Transcriptomics dataset downloads each have a direct relationship to a primary sample data submission corresponding to a specific type I interferon-stimulated host response or type II interferon-stimulated host response experimental study.
- Expression profiling by array (mRNA)
Linked Primary Data Accessions
BioProject Accession: PRJNA417087
GEO Accession: GSE106524 (mRNA transcriptome response)
Acknowledgment of Federal Funding
The data described here was funded in whole or in part by the National Institute of Allergy and Infectious Diseases, of the National Institutes of Health under award number U19AI106772 and is a contribution of the "Modeling Host Responses to Understand Severe Human Virus Infections" Project at Pacific Northwest National Laboratory. Data generated by the Omics-LHV Core for proteomics, metabolomics, and lipidomics analyses for were performed at Pacific Northwest National Laboratory in the Environmental Molecular Sciences Laboratory, a national scientific user facility sponsored by the Department of Energy’s (DOE) Office, operating under the Battelle Memorial Institute for the DOE under contract number DE-AC05-76RLO1830.