Dataset - Omics, Transcriptomics Omics-Lethal Human Viruses, MERS-CoV Experiment MCL005

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson

MERS-CoV Experiment MCL005 Metadata

The purpose of this experiment was to evaluate the human host epigenetic response to MERS-CoV virus infection. Samples were obtained from human lung adenocarcinoma cells (Calu-3) and processed for methylation profiling by high throughput sequencing.

Processed MeDIP-Seq Data Unavailable

Reference Citation

1. Eisfeld, A.J., Anderson, L.N., Fan, S. et al. A compendium of multi-omics data illuminating host responses to lethal human virus infections. Sci Data 11, 328 (2024). https://doi.org/10.1038/s41597-024-03124-3

Linked Primary Data Accessions

NCBI BioProject: PRJNA428998

GEO Series: GSE108882*

*Raw measurement data has primary data publication pubmed:29339515

Acknowledgment of Federal Funding

The data described here was funded in whole or in part by the National Institute of Allergy and Infectious Diseases, of the National Institutes of Health under award number U19AI106772 and is a contribution of the "Modeling Host Responses to Understand Severe Human Virus Infections" Project at Pacific Northwest National Laboratory. Data generated by the Omics-LHV Core for proteomics, metabolomics, and lipidomics analyses for were performed at Pacific Northwest National Laboratory in the Environmental Molecular Sciences Laboratory, a national scientific user facility sponsored by the Department of Energy’s (DOE) Office, operating under the Battelle Memorial Institute for the DOE under contract number DE-AC05-76RLO1830. 

Data Licensing

CC BY 4.0 (dataset DOI downloads), CC0 1.0 (PNNL DataHub policy default)