Category
Description
This data package consists of data from human islets and EndoC-βH1 cells treated with IFNα for 2, 8, or 24 h and submitted to RNA-seq (human islets: n=6 & EndoC-βH1: n=5) and ATAC-seq (n=4). In parallel, a batch of cells (n=4) had proteomics, lipidomics, and metabolomics performed in the same samples (Table 1)
Data contributors:
Xiaoyan Yi, Arturo Roca-Rivada & Décio L. Eizirik: ULB Center for Diabetes Research, Medical Faculty, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Ernesto S. Nakayasu, Jennifer Kyle, Young-Mo Kim, Soumyadeep Sarkar & Thomas O. Metz: Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, 99354, USA.
Data repositories:
RNA-seq: Human GSE148058 & GSE133218
ATAC-seq: GSE133219
Proteomics: PXD011902
Lipidomics: MSV000086174
Metabolomics: https://osf.io/93rux
Publication: PMID 32444635