Dataset - Proteomics, Metabolomics, Lipidomics, RNA-Seq (mRNA,miRNA) Multi-omics data resource: Data package 3 (Pck003)

This data package consists of data from human islets and EndoC-βH1 cells treated with IFNα for 2, 8, or 24 h and submitted to RNA-seq (human islets: n=6 & EndoC-βH1: n=5) and ATAC-seq (n=4). In parallel, a batch of cells (n=4) had proteomics, lipidomics, and metabolomics performed in the same samples (Table S1)

Data contributors:

Xiaoyan Yi, Arturo Roca-Rivada & Décio L. Eizirik: ULB Center for Diabetes Research, Medical Faculty, Université Libre de Bruxelles, Brussels, 1070, Belgium.

Ernesto S. Nakayasu, Jennifer E. Kyle, Young-Mo Kim, & Thomas O. Metz: Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, 99354, USA.

Data repositories:

HI RNA-seq: GSE148058 & SRP255175

EndoC-βH1 RNA-seq: GSE133218 & SRP211834

ATAC-seq: GSE133219 & SRP211833

Proteomics: PXD011902

Lipidomics: MSV000102833

Metabolomics: MSV000102833

Publication: PMID 32444635