Dataset - Proteomics, RNA-Seq (mRNA,miRNA) Multi-omics data compendium: Data package 8 (Pck008)

It consists of human islets (n=5) treated with IFNγ + IL-1β with or without difluoromethylornithine (DFMO) and submitted to RNA-seq and proteomics analysis (Table 1). DFMO is an inhibitor of ornithine decarboxylase (ODC), an enzyme of the polyamine pathway. Therefore, this treatment was done to study if inhibiting the polyamine synthesis improves β-cell dysfunction.

Data repositories:

RNA-seq: GSE226888

Proteomics: MSV000091431

Publication: PMID 37918404