Dataset - RNA-Seq (mRNA,miRNA) Multi-omics data compendium: Data package 16 (Pck016)

This data package consists of data from sets of β-TC-3 cells (n=3) treated with IL-1β + IFNγ + TNFα for 24 h with or without ML351 and submitted to RNA-seq (Table 1). ML351 is an inhibitor of 12-lipoxygenase, an enzyme that produces 12-HETE. Therefore, this treatment was done to study whether inhibiting 12-HETE synthesis improves β-cell dysfunction.

Data contributors: 

Sarah Tersey & Raghavendra Mirmira: Kovler Diabetes Center and Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.

Publication: PMID 28842399