Dataset - RNA-Seq (mRNA,miRNA) Multi-omics data compendium: Data package 17 (Pck017)

It consists of MIN6 cells (n=3) treated with IFNγ + IL-1β + TNFα with or without DFMO or N1,N11-diethylnorspermine (DENSpm) and submitted to RNA-seq (Table 1). DENSpm is an inhibitor of ornithine decarboxylase (ODC) and polyamine oxidase (PAOX), both enzymes in the polyamine pathway. Therefore, this treatment was performed to determine whether inhibiting polyamine synthesis via distinct enzymes improves β-cell dysfunction.

Data repository: GSE242725

Publication: PMID 38195178