Category
Description
It consists of MIN6 cells (n=4) treated with IL-1β + IFNγ + TNFα for 24 h post-RNAi targeting ADP-ribosylhydrolase ARH3 (Adprhl2), and submitted to proteomics analysis (Table 1). ARH3 is a hydrolase that keeps cellular ADP-ribosylation levels in check and is regulated by omega-3 FA to protect β cells from cytokine-induced apoptosis. Therefore, this RNAi treatment was performed to further investigate the mechanism of ARH3-mediated β-cell protection.
Data repository: PXD021501
Publication: PMID 39648458
English