Description
This data package comprises omics datasets from human pancreatic islets treated with IL-1β + IFNγ or with estrogen (E2) for 18 h. Two RNA-seq datasets are available: the first is a discovery dataset involving human islets treated with or without IL-1β + IFNγ for 18 hours; the second is a validation dataset, where human islets are treated with or without IL-1β + IFNγ or E2 for 18 hours. DIA proteomic analysis was performed on the same validation dataset samples.
Data contributors:
Kiersten L. Webster, Sarah Tersey & Raghavendra G. Mirmir: Kovler Diabetes Center and Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.
Soumyadeep Sarkar, Raghavendra Mirmira, Ernesto S. Nakayasu: Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, 99354, USA.
Data repository:
RNA-seq: GSE310965
Proteomics: MSV000101892
Publication: PMID 41279069