Description
This data set consists of sets of mouse β-TC-3 cells (n=3) treated with IL-1β + IFNγ + TNFα for 24 h with or without ML351 and submitted to RNA-seq. ML351 is an inhibitor of 12-lipoxygnease, an enzyme that produces 12-HETE. Therefore, this treatment was done to study whether inhibiting 12-HETE synthesis improves β-cell dysfunction.
Data contributors:
Sarah A. Tersey & Raghavendra G. Mirmira: Kovler Diabetes Center and Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.
Publication: PMID: 28842399
English