AI/ML Ready Datasets for Type 1 Diabetes

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Principal Investigator

Description

Machine learning is a core technology that is rapidly advancing within type 1 diabetes (T1D) research. Our Human Islet Research Network (HIRN) grant is studying early cellular response initiating β cell stress in T1D through the generation of heterogenous low- and high-throughput molecular measurements, which are well suited for use as AI/ML ready datasets, as well as the development of generalized software solutions to transform disparate data into common formats with appropriate metadata for AI/ML. The data packages developed will focus formats that can address challenges in pre-processing (e.g., imputation), feature extraction, and other gaps in the processing of single- and multi-omics datasets that can be addressed through AI/ML methods for both small and large sample sizes. 

We provide AI/ML ready omics datasets that are at various stages of data processing that they are amenable to (1) new methods to improve the pre-processing of single- and multi-omics datasets and (2) predictive modeling of endpoints of T1D.

Descriptions and dataset links for each of the following research projects can be found at the following urls:

 

Projects (3)

The Environmental Determinants of Diabetes in the Young (TEDDY) study is searching for factors influencing the development of type 1 diabetes (T1D) in children. Research has shown that there are certain genes that correlate to higher risk of developing T1D, but not all children with these genes...

  1. Datasets

    1

The Diabetes Autoimmunity Study in the Young (DAISY) seeks to find environmental factors that can trigger the development of type 1 diabetes (T1D) in children. DAISY follows children with high-risk of developing T1D based on family history or genetic markers. Genes, diets, infections, and...

  1. Datasets

    1

The Human Islet Research Network (HIRN) is a large consortia with many research projects focused on understanding how beta cells are lost in type 1 diabetics (T1D) with a goal of finding how to protect against or replace the loss of functional beta cells. The consortia has multiple branches of...

  1. Datasets

    1

Project status

Inactive
English
Datasets (3)