Description
Gas chromatography-mass spectrometry-based metabolomics to identify molecular signatures of Type 1 Diabetes (T1D) in urine. We utilize three cohorts in different stages post-diagnosis: (1) new onset, (2) within one year of diagnosis and (3) after 6 years of diagnosis.
There were 91 metabolites identified in all three datasets with complete data represented in each cohort dataset.
Cohort 1 (CNMC):
- 32 T1D cases; 32 healthy controls siblings
Cohort 2 (BDCD):
- 27 T1D cases; 27 healthy controls siblings
Cohort 3 (IUSOM):
- 12 T1D cases; 20 healthy controls
- Cases and controls matched on sex and age
English