The purpose of this MERS experiment was to obtain samples for omics analysis in primary human microvascular endothelial cells infected with wild type MERS-coronavirus MERS-CoV (icMERS-CoV, EMC2012).
Overall Design: Human airway epithelial cells were infected in a multiplicity of 5 PFU per cell. Infected samples were collected in quintuplet and time-matched with mocks samples in parallel. Transcriptome and Mass spectrometry sample time points: 0, 12, 24, 36, and 48 hrs post-infection.
MERSCOV004.0P references the write up of the experimental procedure.
Processed Omics Data (available at download button):
Dataset downloads contain one or more statistically processed data file related to a lipidomic, transcriptomic, metabolomic, and/or proteomic dataset collection associated with an icMERS experimental study.
Related Experimental Data
GEO: GSE86530 (mRNA transcriptome response)
MassIVE: MSV000083534 (lipidome response), MSV000081890 (metabolome response), MSV000083530 (proteome response)