The purpose of this MERS experiment was to obtain samples for omics analysis in primary human microvascular endothelial cells infected with wild type MERS-CoV (icMERS).
Overall Design: Human airway epithelial cells were infected in a multiplicity of 5 PFU per cell. Infected samples were collected in quintuplet and time-matched with mocks samples in parallel. Sample time points used were: 0, 12, 24, 36, and 48 hrs post-infection.
MERSCOV002.0P references the write up of the experimental procedure.
Processed Omics Data (available at download button):
Dataset downloads contain one or more statistically processed data file related to a lipidomic, transcriptomic, metabolomic, and/or proteomic dataset collection associated with an icMERS experimental study.
Related Experimental Data
BioProject: PRJNA315199, PRJNA315195
GEO: GSE79218 (mRNA transcriptome response), GSE79216 (mRNA transcriptome response)
MassIVE: MSV000081047 (lipidome response), MSV000079702 (metabolome response), MSV000079703 (proteome response)