Influenza A Experiment ICL102
The purpose of this experiment was to evaluate the human host response to Influenza A wild-type (H7N9) virus and mutant viruses. Sample data was obtained for human lung adenocarcinoma cell line (Calu-3) infected with WT H7N9 (A/Anhui/1/2013; AH1) and NS1-L103F/I106M for mRNA, miRNA, proteomics, lipidomics, and metabolomics data analysis.
Processed Omics Data (available at download button):
Dataset downloads contain one or more statistically processed data files related to a transcriptomic, proteomic, metabolomic, and/or lipidomic dataset collection associated with an Influenza A virus experimental study.
- Expression profiling by array (mRNA)
- Non-coding RNA profiling by array (miRNA)
- Protein quantification by liquid chromatography mass spectrometry (LC-MS)
- Lipid quantification by liquid chromatography mass spectrometry (LC-MS)
- Metabolite quantification by liquid chromatography mass spectrometry (GC-MS)
Related Experimental Data
GEO SuperSeries: GSE65575 (Modeling Host Responses to Understand Severe Human Virus Infections)
Viral Provenance: 10.1038/nature12392
Acknowledgment of Federal Funding
The data described here was funded in whole or in part by the National Institute of Allergy and Infectious Diseases, of the National Institutes of Health under award number U19AI106772, and is a contribution of the "Modeling Host Responses to Understand Severe Human Virus Infections" Project at Pacific Northwest National Laboratory. Data generated by the Omics-LHV Core for proteomics, metabolomics, and lipidomics analyses for were performed at Pacific Northwest National Laboratory in the Environmental Molecular Sciences Laboratory, a national scientific user facility sponsored by the Department of Energy’s (DOE) Office, operating under the Battelle Memorial Institute for the DOE under contract number DE-AC05-76RLO1830.