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Experiment MCL003


The purpose of this MERS experiment was to obtain samples for omics analysis of human Calu-3 cell response to treated with wild-type icMERS-CoV and mockulum. For proteomics, lipidomics, and metabolomics data from the Calu-3 cells infected with MERS-CoV, the quantitative data profiles were evaluated for extreme outlier behavior using MPLEX protocol.

Overall Design: 3 mockulum treated and 9 MERS-CoV treated (18 hrs).

Processed Omics Data (available at download button):

Dataset downloads contain one or more statistically processed data file related to a lipidomic, transcriptomic, metabolomic, and/or proteomic dataset collection associated with an icMERS experimental study. 





Related Experimental Data

PRIDE Accession: PXD002360PXD002359, PXD002358

MassIVE:  MSV000079154 (lipidome response),  MSV000080022 (metabolome response), MSV000079152 (proteome response)

DOI:  10.1128/mSystems.00043-16

Projects (2)
Omics-Lethal Human Virus, MERS-CoV
NIAID Modeling Host Responses to Understand Severe Human Virus Infections Research Program Processed Data
People (3)

Lindsey Anderson’s research has been dedicated to the identification and characterization of novel, targeted and non-targeted, functional metabolic interactions using a high-throughput systems biology and computational biology approach. Her expertise in functional metabolism and multidisciplinary...

Dr. Jason McDermott, senior research scientist, has extensive research experience in molecular and structural virology and data resource design, data integration and prediction of biological networks, bridging experimental and computational biology. Currently, his research interests include data...

Dr. Katrina Waters is the division director for Biological Sciences at the Pacific Northwest National Laboratory. Waters has a Ph.D. in biochemistry and more than 15 years of experience in microarray and proteomics data analysis. Her research interests are focused on the integration of genomics...