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Omics-LHV, West Nile

Experiment WSE001


The purpose of this West Nile experiment was to obtain samples for omics analysis in mouse (C57BL6/JAX) serum of mock-treated (Koolaid) and/or drug treated (3Abx; Ampicillin, Vancomycin, and Neomycin) in response to wild-type West Nile virus (WNV-NY99 382) infection. 

Overall Design: Treatment started two week before inoculation and throughout infection. C57BL6/JAX mice were inoculated at 8 weeks of age at a dose of 100 FFU. Infected samples were then collected in replicate (2-5) fro each collection. Mice were given the following doses: mock (Koolaid) = 20 g/L; treated (3Abx) = 20 g/L; Ampicillin 1g/L, Neomycin 1g/L, Vancomycin 0.5 g/L. Time points used were: D-1 before and D3 after inoculation.

Processed Omics Data (available at download button):

Dataset downloads contain one or more statistically processed data file related to a lipidomic, transcriptomic, metabolomic, and/or proteomic dataset collection associated with a West Nile experimental study. 





Projects (2)
Omics-Lethal Human Virus, West Nile
NIAID Modeling Host Responses to Understand Severe Human Virus Infections Research Program Processed Data
People (3)

Lindsey Anderson’s research has been dedicated to the identification and characterization of novel, targeted and non-targeted, functional metabolic interactions using a high-throughput systems biology and computational biology approach. Her expertise in functional metabolism and multidisciplinary...

Dr. Jason McDermott, senior research scientist, has extensive research experience in molecular and structural virology and data resource design, data integration and prediction of biological networks, bridging experimental and computational biology. Currently, his research interests include data...

Dr. Katrina Waters is the division director for Biological Sciences at the Pacific Northwest National Laboratory. Waters has a Ph.D. in biochemistry and more than 15 years of experience in microarray and proteomics data analysis. Her research interests are focused on the integration of genomics...