https://www.nih.gov/about-nih/what-we-do/mission-goals NIH’s mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The goals of the agency are: to foster...

The Human Islet Research Network (HIRN) is a large consortia with many research projects focused on understanding how beta cells are lost in type 1 diabetics (T1D) with a goal of finding how to protect against or replace the loss of functional beta cells. The consortia has multiple branches of...

The influence of tidal inundation dynamics on below ground carbon pools is poorly understood across coastal terrestrial-aquatic interface (TAI) ecosystems. The dynamic environmental conditions of tidally-influenced landscapes, the chemically complex nature of carbon compounds, the diverse nature of...

The Phenotypic Response of the Soil Microbiome to Environmental Perturbations Project (Soil Microbiome SFA) at Pacific Northwest National Laboratory is a Genomic Sciences Program Science Focus Area (SFA) Project operating under the Environmental Microbiome Science Research Area. The Soil Microbiome...

The Predicting Ecosystem Resilience through Multiscale Integrative Science (PREMIS) database was generated to mechanistically understand how feedbacks across scales, from molecular to plant to plant populations and communities to ecosystems, govern the resilience of system functions to elevated CO2...

The EyeSea underwater video dataset was assembled for developing algorithms for detecting fish in real world underwater video data. The data were recorded as part of environmental monitoring efforts at three different water power sites.

The objective of Terrestrial-Aquatic Interface (TAI) research in PREMIS is to understand the factors governing C and nutrient movement and transformation through the TAI, and their sensitivities to inundation and salinity within coastal watersheds.

Accurate characterization of the global downward shortwave (SW) and photosynthetically active radiation (PAR) is fundamental for Earth system modeling and global change research. Combined with a machine-learning method, we used the Earth Polychromatic Imaging Camera (EPIC) data onboard the Deep...

This project is an interdisciplinary collaboration supported by US DOE Office of Science's Scientific Discovery through Advanced Computing (SciDAC) program. The project addresses a crucial but largely overlooked source of error in the Energy Exascale Earth System Model (E3SM) and other atmosphere...

The PNNL-SERDP database was constructed by PNNL to generate the quantitative infrared spectra of gases associated with biomass burning; the reference data are to allow detection and quantification of such gases via infrared absorption spectroscopy. Candidates for the database were selected based on...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to MERS-CoV Virus Infection Background Middle East Respiratory Syndrome coronavirus ( MERS-CoV ), part of the Coronaviridae family, is classified as a Category C priority pathogen by the National Institute...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Ebola Virus Infection Background Ebola virus ( EBOV ) is a high risk biological agent, belonging to the Flaviviridae family, and is classified as a Category A priority pathogen by the National Institute...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to West Nile Virus Infection Background West Nile virus ( WNV ) belongs to the mosquito-borne Flaviviridae family and is classified as a Category A priority pathogen by the National Institute of Allergy and...

Clinical Proteomic Tumor Analysis Consortium (CPTAC) ovarian cancer proteogenomics project. Characterization of tumors using proteomics and phosphoproteomics to identify signatures of drug resistance and characterize pathways associated with tumor versus normal tissue.

Coastal landscapes are increasingly exposed to seawater due to sea level rise and extreme weather events. The biogeochemical responses of these vulnerable ecosystems are poorly understood, limiting our ability to predict how their role in global biogeochemical cycles will shift under future...