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Dataset
Omics-Lethal Human Viruses, Ebola Experiment EIHH001

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EIHH001 This experiment evaluated Immortalized Human Hepatocyte ( IHH ) cell line host response to wild-type Ebola viruses Zaire Ebola (ZEBOV '76) and Reston Ebola (REBOV '08) viral infection. Processed Transcriptome...

Biology
Human Health
Integrative Omics
Dataset
Omics-Lethal Human Viruses, Ebola Experiment EIHH002

Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EIHH002 This experiment evaluated Immortalized Human Hepatocyte ( IHH ) cell line host response to response to genetically-reconstructed Zaire Ebola virus infection. Processed Transcriptome Data Unavailable

Biology
Human Health
Integrative Omics
Publication
Selection, Succession, and Stabilization of Soil Microbial Consortia
Soil microorganisms play fundamental roles in cycling of soil carbon, nitrogen, and other nutrients, yet we have a poor understanding of how soil microbiomes are shaped by their nutritional and physical environment. In this study, we investigated the successional dynamics of a soil microbiome during...
Earth System Science
Biology
Publication
Draft Genome of Fusarium sp. strain DS 682, a novel Fungal isolate from the Grass Rhizosphere
The novel fungal strain, Fusarium sp. DS 682, was isolated from the rhizosphere of the perennial grass, Bouteloua gracilis , at the Konza Prairie Biological Station in Kansas. This fungal strain is common across North American grasslands and is resilient to environmental fluctuations. The draft...
Earth System Science
Biology
Dataset
Omics-Lethal Human Viruses, MERS-CoV Experiment MDC001

MERS-CoV Experiment MDC001 Processed Omics Data Unavailable This experiment evaluated primary human dendritic cells infected with a wild type MERS-CoV (icMERS) virus. Related Experimental Data BioProject: PRJNA315103 GEO: GSE79172 (mRNA transcriptome response) Acknowledgment of Federal Funding The...

Biology
Human Health
Integrative Omics
Publication
Terabase Metagenome Sequencing of Grassland Soil Microbiomes
As part of the Pacific Northwest National Laboratory’s (PNNL) Science Focus Area program, we are investigating the impact of environmental change on microbial community function in grassland soils. Three grassland soils, representing different moisture regimes, were selected for ultra-deep...
Earth System Science
Biology
Publication
Development and Analysis of a Stable, Reduced Complexity Model Soil Microbiome
The soil microbiome is central to the cycling of carbon and other nutrients and to the promotion of plant growth. Despite its importance, analysis of the soil microbiome is difficult due to its sheer complexity, with thousands of interacting species. Here, we reduced this complexity by developing...
Biology
Earth System Science
Dataset
Omics-Lethal Human Viruses, Influenza A Experiment IM104

Influenza A Experiment IM104 Processed Omics Data Unavailable This Influenza experiment evaluated mouse lung expression after etoposide treatment and infection with a pandemic H1N1 influenza strain. Related Experimental Data BioProject: PRJNA382278 GEO: GSE97555 (mRNA transcriptome response)...

Biology
Human Health
Integrative Omics
Project
Omics Lethal Human Viruses Project Profiling of the Host Response to Ebola Virus Infection, Processed Experimental Dataset Catalog

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Ebola Virus Infection Background Ebola virus ( EBOV ) is a high risk biological agent, belonging to the Flaviviridae family, and is classified as a Category A priority pathogen by the National Institute...

Biology
Human Health
Integrative Omics

  1. Datasets

    6
Project
Omics Lethal Human Viruses Project Profiling of the Host Response to Influenza A Virus Infection, Processed Experimental Dataset Catalog

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background Influenza A virus ( IAV ) is a high risk biological agent belonging to the Orthomyxoviridae family is classified as a Category C priority pathogen by the National...

Biology
Human Health
Integrative Omics

  1. Datasets

    8
Project
Omics Lethal Human Viruses Project Profiling of the Host Response to MERS-CoV Infection, Processed Experimental Dataset Catalog

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to MERS-CoV Virus Infection Background Middle East Respiratory Syndrome coronavirus ( MERS-CoV ), part of the Coronaviridae family, is classified as a Category C priority pathogen by the National Institute...

Biology
Human Health
Integrative Omics

  1. Datasets

    15
Project
NIAID Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...

Biology
Human Health
Integrative Omics

  1. Datasets

    45
Project
Omics Lethal Human Viruses Project Profiling of the Host Response to West Nile Virus Infection, Processed Experimental Dataset Catalog

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to West Nile Virus Infection Background West Nile virus ( WNV ) belongs to the mosquito-borne Flaviviridae family and is classified as a Category A priority pathogen by the National Institute of Allergy and...

Biology
Human Health
Integrative Omics

  1. Datasets

    11
Person
Kristin E Burnum-Johnson

Biography Kristin Burnum-Johnson is a senior scientist and team lead of the Biomolecular Pathways team at PNNL. Burnum-Johnson earned her PhD in Biochemistry from Vanderbilt University with Professor Richard M. Caprioli and then completed a postdoctoral fellowship at PNNL with Dr. Richard D. Smith...

Scientific Discovery
Integrative Omics
Person
Vivian Lin

PerCon SFA, Co-Investigator Vivian Lin earned her PhD in organic chemistry from the University of California, Berkeley with Professor Chris Chang, developing fluorescent probes for imaging redox active small molecules. Afterward, she traveled to Switzerland for a postdoctoral fellowship in the...

Scientific Discovery
Biology
Chemistry