Created on 2024-10-15T19:55:00+00:00 by LN Anderson ; Last updated 2024-11-13T15:01:44+00:00 and is pending public release before or by 2025-10-01. Human Liver Epithelium Response to HCoV-229E Infection Epigenomics (ACS-DP4) The purpose of this experiment was to evaluate how wild-type Human...
Created on 2024-10-15T19:55:00+00:00 by LN Anderson ; Last updated 2024-11-13T15:01:44+00:00 and is pending public release before or by 2025-10-01. Human Primary Airway Epithelium Response to HCoV-229E Infection Transcriptomics (ACS-DP3) The purpose of this experiment was to evaluate the human host...
Created 2024-09-17T19:19:38+00:00 by LN Anderson ; Last updated 2024-10-17T17:30:32+00:00 and is pending public release. Human A549 and MRC5 Cell Response to HCoV-229E Infection Transcriptomics (ACS-DP1) The purpose of this experiment was to evaluate the human host cellular response to wild-type...
Last updated on 2024-10-04T19:31:35+00:00 by LN Anderson Activity-Based Probe Fluorescence-Activated Cell Sorting (ABP-FACS) of Soil Microbes (NR-DP0) Soil samples were incubated with either 0.2% cellobiose for three days or 0.2% xylan for nine days. Microbes were extracted from the soil matrix...
MERS-CoV Experiment MDC001 Processed Omics Data Unavailable This experiment evaluated primary human dendritic cells infected with a wild type MERS-CoV (icMERS) virus. Related Experimental Data BioProject: PRJNA315103 GEO: GSE79172 (mRNA transcriptome response) Acknowledgment of Federal Funding The...
Coronaviruses (CoV) emerge suddenly from animal reservoirs to cause novel diseases in new hosts. Discovered in 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) is endemic in camels in the Middle East and is continually causing local outbreaks and epidemics. While all three newly...
The research goal of this project is to identify and control host functions hijacked during viral infection through use of PNNL ‘omics technologies and modeling capabilities.
Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death. Here, we present experimental methods and multi-omics data capture approaches representing the global host...
PerCon SFA, Co-Investigator Vivian Lin earned her PhD in organic chemistry from the University of California, Berkeley with Professor Chris Chang, developing fluorescent probes for imaging redox active small molecules. Afterward, she traveled to Switzerland for a postdoctoral fellowship in the...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...