Project - Research & Development Manipulation of Host Signature Expression Following Respiratory Virus Infection

Principal Investigator
Amy Sims
Predictive Phenomics
TA2
Biological Systems
High Throughput Sequencing
Lethal Human Viruses
HCoV-299E
Host Immune Response
Homo sapiens
Chemical & Biological Signatures Science
Human Health

The research goal of this project is to identify and control host functions hijacked during viral infection through use of PNNL ‘omics technologies and modeling capabilities.

Projects (1)
Project
Predictive Phenomics Initiative Project Dataset Catalog Collection

The Predictive Phenomics Science & Technology Initiative (PPI) at Pacific Northwest National Laboratory are tackling the grand challenge of understanding and predicting phenotype by identifying the molecular basis of function and enable function-driven design and control of biological systems...

Renewable Energy
Scientific Discovery
Biology
Human Health
Integrative Omics
Computational Mathematics & Statistics
Data Analytics & Machine Learning

  1. Datasets

    17

Project status

Inactive
English
Datasets (5)
Human A549 and MRC5 Cell Response to HCoV-229E Infection Transcriptomics (ACS-DP1)
Human Host Cellular Response to HCoV-229E Infection Multi-Omics (ACS-JM-DP2)
Human Primary Airway Epithelium Response to HCoV-229E Infection Transcriptomics (ACS-DP3)
Human Liver Epithelium Response to HCoV-229E Infection Epigenomics (ACS-DP4)
Human Cellular Response to HCoV-229E Infection Limited Proteolysis Structural Proteomics (JM-ACS-DP5)
People (1)
Amy Sims

Amy Sims, PhD is a Biomedical Scientist in the Chemical and Biological Signatures Division of the National Security Directorate at the Pacific Northwest National Laboratory (PNNL) in Richland, WA. She earned her Ph.D. from Vanderbilt University Medical Center and worked with Ralph Baric, PhD at the...