Omics-LHV, West Nile
The purpose of this West Nile experiment was to obtain samples for omics analysis in mouse popliteal draining lymph nodes (DLN) infected with wild-type West Nile virus (WNV; WNV-NY99 382), and mutant WNV-E218A (WNV-NY99 382 E218A 2 nt).
Overall Design: Mice were inoculated with West Nile Virus (WNV) in both hind footpads using a dose of 100 FFU. Draining lymph nodes (DLN) are collected from both hind legs for a total of 2 samples. For mock inoculated mice, DLN from two mice were pooled for a total of 4 samples.Infected samples were then collected in quintuplet in addition to time-matched mocks in parallel (in triplicate) with infected samples. Time points used were: 1, 2, 4, and 6 days post-infection.
See Experiment WLN002 for corresponding transcriptome analyses.
Processed Omics Data (available at download button):
Dataset downloads contain one or more statistically processed data file related to a lipidomic, transcriptomic, metabolomic, and/or proteomic dataset collection associated with a West Nile experimental study.
Related Experimental Data
MassIVE: MSV000080354 (lipidome response), MSV000080021 (metabolome response), MSV000080024 (proteome response)