LIQUID Software Overview LIQUID provides users with the capability to process high throughput data and contains a customizable target library and scoring model per project needs. The graphical user interface provides visualization of multiple lines of spectral evidence for each lipid identification...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to MERS-CoV Virus Infection Background Middle East Respiratory Syndrome coronavirus ( MERS-CoV ), part of the Coronaviridae family, is classified as a Category C priority pathogen by the National Institute...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Ebola Virus Infection Background Ebola virus ( EBOV ) is a high risk biological agent, belonging to the Flaviviridae family, and is classified as a Category A priority pathogen by the National Institute...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background Influenza A virus ( IAV ) is a high risk biological agent belonging to the Orthomyxoviridae family is classified as a Category C priority pathogen by the National...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Interferon-Stimulated Response to Virus Infection Background The human host Interferon ( IFN ) alpha, beta, and gamma participate in the body's natural immune response to lethal virus infection and disease. The...

Biography Young-Mo Kim is a senior bioanalytical chemist at PNNL. He received his PhD from Pohang University of Science and Technology in the School of Environmental Science and Engineering, studying analysis of metabolites during the bacterial and fungal degradation of xenobiotic substrates using...

Biography Carrie Nicora is a senior research scientist (chemist III) at PNNL, specializing in high-throughput scientific research sample management using modular automation techniques for processing a wide range of biological specimens for proteomic, metabolomic, and lipidomic analysis. She is an...

Biography Kristin Burnum-Johnson is a senior scientist and team lead of the Biomolecular Pathways team at PNNL. Burnum-Johnson earned her PhD in Biochemistry from Vanderbilt University with Professor Richard M. Caprioli and then completed a postdoctoral fellowship at PNNL with Dr. Richard D. Smith...

Biography Ernesto Nakayasu is a senior research scientist focused on understanding molecular mechanisms of diseases. Nakayasu has been applying systems biology and mass spectrometry-based omics measurements to study how pathogens and metabolic alterations cause human diseases; the goal is to...

Biography Dr. Smith's research interests span the development of advanced analytical methods and instrumentation, with particular emphasis on high-resolution separations and mass spectrometry, and their applications in biological and biomedical research. This has included creating and applying new...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MMVE001 The purpose of this experiment was to evaluate the human host response to MERS-CoV (strain EMC-2012) infectious clone (icMERS-CoV) virus infection. Sample data was obtained from primary human microvascular...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MFB003 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (icMERS-CoV) virus infection. Sample data was obtained from primary human fibroblasts and processed for mRNA, proteomics...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MHAE001 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (icMERS-CoV) virus infection. Sample data was obtained from primary human airway epithelial (HAE) cells for mRNA, miRNA...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MFB001 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (icMERS-CoV) virus infection. Sample data was obtained from primary human fibroblasts and processed for mRNA, miRNA...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MFB002 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (icMERS-CoV) virus infection. Sample data was obtained from primary human fibroblasts for mRNA, proteomics, metabolomics...