This data package consists of data from MIN6 cells (n=4) treated with IL-1β + IFNγ + TNFα for 24 h post RNAi targeting 85/88 kDa calcium-independent phospholipase A2 ( Pla2g6 ) and submitted to proteomics analysis ( Table 1 ). Pla2g6 is an enzyme that metabolizes phosphatidylcholine (PCs) into...

This data package consists of data from human islets and EndoC-βH1 cells treated with IFNα for 2, 8, or 24 h and submitted to RNA-seq (human islets: n=6 & EndoC-βH1: n=5) and ATAC-seq (n=4). In parallel, a batch of cells (n=4) had proteomics, lipidomics, and metabolomics performed in the same...

This data package consists of data from MIN6 cells treated with IL-1β + IFNγ + TNFα + palmitate for 24 h and submitted to proteomics analysis, and the same treatment for 8 h for metabolomics analysis (n=4) ( Table 1 ). This experimental design was set to study the possible roles of free fatty acids...

This data package consists of data from parallel experiments compared to Pck001 but performed with EndoC-βH1 cells instead of human islets. Cells were treated with IFNγ + IL-1β for 48 h and submitted to RNA-seq (n=5), ATAC-seq (n=5), DNA methylation (n=5), and H3K27Ac ChIP-seq (n=4). In addition...

This data package consists of data from paired human islets treated with IFNγ + IL-1β for 48 h and submitted to RNA-seq (n=5), ATAC-seq (n=5), UMI-4C18 (n=2 or 3, depending on the viewpoint), and ChIP-seq for histone H3 lysine 27 acetylation (H3K27Ac) (n=4) ( Table 1 ). Islets across the two studies...

This data package consists of data from MIN6 cells (n=4) treated with IL-1β + IFNγ + TNFα and RNAi targeting Poly(ADP)ribosyl polymerase 12 ( Parp12 ) for 24 h and submitted to proteomic analyses ( Table 1 ). PARP12 is an interferon-induced protein known to target viral RNA to stress granules. It...

Please cite as : Mary S. Lipton, William C. Nelson, Hugh McCullough, Montana L. Smith, Sheryl L. Bell, Lisa M. Bramer, Hyun-Seob Song, Kirsten Hofmockel, 2025. Moisture Metaphenome Incubation Analysis Results . [Data Set] PNNL DataHub. https://doi.org/10.25584/3007775 This data is published under a...

RhizoGrid Indexed Sorghum Rhizosphere Multi-Omics pending public release Identification of spatially resolved biomarkers of drought in Sorghum bicolor rhizosphere molecular-microbe interactions using a novel root cartography "RhizoGrid" system for sampling plants under drought and control conditions...

This data package contains processed LC-MS proteomics results and analysis scripts associated with the paper "Assessing Degenerate Peptide Resolution Methods using a Ground Truth Dataset". In this study, we designed an artificial microbial community to create a ground truth, simulated metaproteomic...

This repository contains data and code for the experiments run in the paper "Understanding Generative AI Content with Embedding Models" ( https://arxiv.org/abs/2408.10437 ). DataBase POC: Max Vargas (max.vargas@pnnl.gov) The data is separated by experiment: A. The `stack_exchange` dataset contains a...

Please cite as : Josué A. Rodríguez-Ramos, Amy E. Zimmerman, Ruonan Wu, Sheryl Bell, Trinidad Alfaro, Kirsten Hofmockel, William C. Nelson. 2025. Inter-Kingdom Viral Interactions. [Data Set] PNNL DataHub. https://doi.org/10.25584/2583337 This data is published under a CC0 license . The authors...

Please cite as : Robert E. Danczak, Sheryl Bell, Evan Warburton, Trinidad Alfaro, Kirsten Hofmockel, Amy E. Zimmerman, William C. Nelson, 2025. Prokaryotic and eukaryotic interactions along a moisture gradient . [Data Set] PNNL DataHub. https://doi.org/10.25584/2574929 This data is published under a...

Created 2025-06-03T23:16:59+00:00 by LN Anderson .Currently pending DOI assignment for public release. Integrative SP3 Workflow for Multi-PTM Proteomics Profiling (PPI-TZ-DP0) The purpose of this experiment was to evaluate a new standardized method approach for proteomics sample processing designed...

Data package for Lipids represent a dynamic, yet stable pool of microbially-derived soil carbon This data is published under a CC0 license . The authors encourage data reuse and request attribution by referencing the below citations for the data packages and associated manuscript. Please cite as...

Please cite as : McClure, R. and Janet Jansson. 2025. EVT 16s Data and Large Supplementary Files . [Data Set] PNNL DataHub. https://doi.org/10.25584/2530740. This data is published under a CC0 license . The authors encourage data reuse and request attribution by referencing the above citations for...