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MERS-CoV Experiment MDC001 Processed Omics Data Unavailable This experiment evaluated primary human dendritic cells infected with a wild type MERS-CoV (icMERS) virus. Related Experimental Data BioProject: PRJNA315103 GEO: GSE79172 (mRNA transcriptome response) Acknowledgment of Federal Funding The...

Omics-LHV, MERS Experiment MCL002 The purpose of this MERS experiment was to obtain samples for omics analysis of Calu-3 cell response treated with wild-type MERS-CoV, MERS-CoV mutants and mockulum. Overall Design: 5 replicates at 6 time points (0, 3, 7, 12, 18 and 24 hr.) of 6 conditions (mock...

MERS-CoV Experiment MCL001 The purpose of this experiment was to evaluate the human host cellular response to wild-type Middle Eastern Respiratory Syndrome coronavirus (icMERS) and icMERS-CoV mutants icMERS-CoV-RFP, icMERS-CoV-dNSP16, icMERS-CoV-d4B, and icMERS-CoV-d3 virus infection. Sample time...

Interferon Experiment IFNaHUH001 The purpose of this experiment was to evaluate the human host cellular response to treatment with and without interferon alpha beta (IFNαβ) treatment. Sample time course data was obtained from human hepatoma carcinoma cells (HUH-7) expressing transcriptional...

Interferon Experiment IFNMVE001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to human interferon alpha beta (IFNαβ) or gamma (INFγ) treatment. Sample data was obtained from human primary lung microvascular endothelial (MVE) cells treated with or...

Interferon Experiment IFNFB001 The purpose of this experiment was to evaluate the human host cellular response to interferon alpha beta (IFNαβ) or interferon gamma (IFNγ) treatment. Sample data was obtained from primary human lung fibroblast (FB) cells inoculated with IFNαβ or IFNγ for transcriptome...

Omics-Lethal Human Virus, Interferon Experiment IFNαIHH001 The purpose of this experiment was to evaluate the human host cell response to human interferon α (IFNα) treatment. Sample data was obtained from human IHH (immortalized human hepatocyte) cells for mRNA and miRNA transcriptome data analysis...

Interferon Experiment FNαCL001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to human interferon alpha (IFNα) treatment. Sample data was obtained from human lung adenocarcinoma cells (Calu-3) treated with or without IFNα for mRNA and miRNA...

Omics-LHV Profiling of Host Response to West Nile Virus Infection Background: West Nile virus (WNV) is classified as a Category B priority pathogen, by the National Institute of Allergy and Infectious Diseases (NIAID), and are known to cause severe and even fatal infections in humans where lethal...

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Omics-LHV Profiling of Host Response to Ebola Virus Infection Background: Ebola virus (EBOV) is classified as a Category A priority pathogen, by the National Institute of Allergy and Infectious Diseases (NIAID), and are known to cause severe and even fatal infections in humans where lethal host...

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Omics-LHV Profiling of Host Response to MERS-CoV Virus Infection Background: Middle East Respiratory Syndrome coronavirus (MERS-CoV) is classified as a Category C priority pathogen, by the National Institute of Allergy and Infectious Diseases (NIAID), and are known to cause severe and even fatal...

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Omics-LHV Profiling of Host Interferon-Stimulated Response to Virus Infection Data Reuse & Impact: Omics-LHV PNNL sub-projects provide a never before released comprehensive human interferon response collection of primary and secondary transformation multi-Omics data profiling a series of priority...

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Neisseria gonorrhoeae is a Gram-negative diplococcus that is responsible for the sexually transmitted infection gonorrhea, a high morbidity disease in the United States and worldwide. Over the last several years N. gonorrhoeae strains resistant to antibiotics used to treat this infection have begun...

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Investigation of the successional dynamics of a soil microbiome during 21-weeks of enrichment on chitin and its monomer, N-acetylglucosamine (NAG). Soil community succession was observed and analyzed over time in both a physically heterogeneous soil matrix as well as a homogeneous liquid medium...
Dataset

The data accompanies the manuscript that evaluates salinity-associated shifts in organic C thermodynamics, biochemical transformations, and heteroatom content in a first-order coastal watershed in the Olympic Peninsula of Washington state, USA. The files contain raw data including soil chemical...