MERS-CoV Experiment MDC001 Processed Omics Data Unavailable This experiment evaluated primary human dendritic cells infected with a wild type MERS-CoV (icMERS) virus. Related Experimental Data BioProject: PRJNA315103 GEO: GSE79172 (mRNA transcriptome response) Acknowledgment of Federal Funding The...
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The Sequel II System Sequencer is a high-throughput DNA sequencer machine developed and manufactured by PacBio , and is designed for high throughput, production-scale sequencing laboratories. Originally released in 2015, the Sequel system provides Single Molecule, Real-Time (SMRT) sequencing core...
Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death. Here, we present experimental methods and multi-omics data capture approaches representing the global host...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...
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The Environmental Determinants of Diabetes in the Young (TEDDY) study is searching for factors influencing the development of type 1 diabetes (T1D) in children. Research has shown that there are certain genes that correlate to higher risk of developing T1D, but not all children with these genes...
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The Diabetes Autoimmunity Study in the Young (DAISY) seeks to find environmental factors that can trigger the development of type 1 diabetes (T1D) in children. DAISY follows children with high-risk of developing T1D based on family history or genetic markers. Genes, diets, infections, and...
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Machine learning is a core technology that is rapidly advancing within type 1 diabetes (T1D) research. Our Human Islet Research Network (HIRN) grant is studying early cellular response initiating β cell stress in T1D through the generation of heterogenous low- and high-throughput molecular...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to MERS-CoV Virus Infection Background Middle East Respiratory Syndrome coronavirus ( MERS-CoV ), part of the Coronaviridae family, is classified as a Category C priority pathogen by the National Institute...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Ebola Virus Infection Background Ebola virus ( EBOV ) is a high risk biological agent, belonging to the Flaviviridae family, and is classified as a Category A priority pathogen by the National Institute...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background Influenza A virus ( IAV ) is a high risk biological agent belonging to the Orthomyxoviridae family is classified as a Category C priority pathogen by the National...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to West Nile Virus Infection Background West Nile virus ( WNV ) belongs to the mosquito-borne Flaviviridae family and is classified as a Category A priority pathogen by the National Institute of Allergy and...
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Last updated on 2024-03-03T02:26:52+00:00 by LN Anderson The Thermo Scientific™ Q Exactive™ Plus Mass Spectrometer benchtop LC-MS/MS system combines quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection to deliver exceptional performance and versatility...
The Illumina HiSeq X System Sequencer is a high-throughput DNA sequencer machine developed and manufactured by Illumina , and is designed for high throughput, production-scale sequencing laboratories. Built off the HiSeq 2500 System, harnessing the patterned flow cell technology originally developed...
Last updated on 2024-03-03T02:26:52+00:00 by LN Anderson The Thermo Scientific™ Velos Pro™ Orbitrap Mass Spectrometer instrument data source combines advanced mass accuracy with an ultra-high resolution Orbitrap mass analyzer for increased sensitivity, enabling molecular weight determination for...