Q Exactive Plus Mass Spectrometer


The Thermo Scientific™ Q Exactive™ Plus Mass Spectrometer benchtop LC-MS/MS system [MS:1000494] combines quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection to deliver exceptional performance and versatility. Quadrupole technology optimizes precursor selection and transmission, improving quantitation of low-abundance ions in the most complex matrices. Sophisticated parallel reaction monitoring and data independent analysis provide reproducible quantitation results while delivering complete qualitative confidence. An optional intact protein mode enhances analysis of intact proteins through sophisticated ion beam control and easy collision pressure adjustment, while optional 280,000 maximum resolving power ensures superior ID confidence. The Q Exactive Mass Spectrometer is equally useful for untargeted or targeted screening and a broad range of qualitative and quantitative applications in top-down proteomics and Lipidomics applications.

Data Source Contributions

Instrument Data Source Profile

Instrument Name:      Q Exactive Plus Mass Spectrometer [MS:1002634]

Model:                         Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer

Platform:                     Q Exactive Plus (LC-HMS with MS/MS), with optional HCD [MS:1002481]

Data Type:                   HMS, HMS-HCD-HMSn, HMS-HMSn

Instrument Group:      Mass spectrometryLiquid Chromatography-Mass Spectrometry, High Resolution Mass Spectrometry

                                      High-Energy Collision-Induced Dissociation

Topic Areas:                OmicsProteomics


Explore this capability and more at EMSL's Omics & Mass Spectrometer (MS) resource page under Omics and Mass Spectrometry for Bottom-Up Proteomics. For a list of complimentary mass spectrometry data process software and analytical workflows, visit https://zenodo.org/communities/pnnl


Federal Acknowledgements

This work was supported in part by the Earth and Biological Sciences Directorate (EBSD) at Pacific Northwest National Laboratory (PNNL), a multiprogram national laboratory managed by the Battelle Memorial Institute, operating under the U.S. Department of Energy (DOE) contract DE-AC05-76RL01830. User capabilities described here reflect collaborations with the Environmental Molecular Sciences Laboratory (EMSL), a DOE Office of Science (SC-3) user facility operating under the Contract No. DE-AC05-76RL01830.

Terms of Use

Recommendation guidelines provided by the DOE Office of Science can be accessed at the SC Funding Opportunities & Acknowledgements homepage. For additional information regarding user capability data release, visit the SC Digital Data Management Resources at User Facilities for more information.

EMSL Funding Acknowledgment

Scientists who publish results of research using EMSL resources, capabilities, and resulting data are required to include an acknowledgment of EMSL Policies in any publications. Learn more about user facility data management resources at the Office of Science Program page.

Projects (7)

Reusable Digital Data Lifecycle Downloads for Omics-Lethal Human Virus Systems Biology The Omics-LHV Systems Virology project was one of four projects, funded by the NIAID Systems Biology for Infectious Diseases Research Program (funded from 2008-2013), was established in developing and validating...

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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases ( NIAID ) "Modeling Host...

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The Phenotypic Response of the Soil Microbiome to Environmental Perturbations Project (Soil Microbiome SFA) at Pacific Northwest National Laboratory is a Genomic Sciences Program Science Focus Area (SFA) Project operating under the Environmental Microbiome Science Research Area. The Soil Microbiome...

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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background Influenza A virus (IAV) is a high risk biological agent, classified as a Category C priority pathogen ( Orthomyxoviridae ) by the National Institute of Allergy and...

  1. Datasets


Omics-LHV Systems Biology Modeling Host Response to Severe Acute Respiratory Syndrome (SARS) Infection The Systems Virology project was one of four systems biology contracts funded by the NIAID Systems Biology for Infectious Diseases Research Program from 2008-2013. The Systems Biology for...

  1. Datasets

The Biomedical Resilience & Readiness in Adverse Operating Environments (BRAVE) Project develop new capabilities to improve health and performance of first responders in adverse operating environments common to national defense. The BRAVE project analyze biological samples, collect physiological...
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Last updated on 2023-11-09T21:18:57+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Ebola Virus Infection Background Ebola virus (EBOV) is a high risk biological agent, classified as a Category A priority pathogen ( Flaviviridae ) by the National Institute of Allergy and Infectious...

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Datasets (6)
Publications (1)
Arunima Bhattacharjee
Lindsey N. Anderson
Dr William C Nelson
Ari Jumpponen
Janet K. Jansson
Kirsten Hofmockel
Dr Christopher R Anderton
People (1)

Lindsey Anderson’s research has been dedicated to the identification and characterization of novel, targeted and non-targeted, functional metabolic interactions using a high-throughput systems biology and computational biology approach. Her expertise in functional metabolism and multidisciplinary...

Methods (1)
Institutions (1)
Software (1)
Resources (1)