Q Exactive Plus Mass Spectrometer

Description

Identify, quantify, and confirm more compounds rapidly and with confidence using the Thermo Scientific™ Q Exactive™ Plus Mass Spectrometer. This benchtop LC-MS/MS system combines quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection to deliver exceptional performance and versatility. Quadrupole technology optimizes precursor selection and transmission, improving quantitation of low-abundance ions in the most complex matrices. Sophisticated parallel reaction monitoring and data independent analysis provide reproducible quantitation results while delivering complete qualitative confidence. An optional intact protein mode enhances analysis of intact proteins through sophisticated ion beam control and easy collision pressure adjustment, while optional 280,000 maximum resolving power ensures superior ID confidence. The Q Exactive Mass Spectrometer is equally useful for untargeted or targeted screening and a broad range of qualitative and quantitative applications in top-down proteomics and Lipidomics applications.

Data Source Contributions

Instrument Data Source Profile

Instrument Name:      Q Exactive Plus Mass Spectrometer

Model:                         Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer

Platform:                     Q Exactive Plus (LC-HMS with MS/MS, optional HCD)

Data Type:                   HMS, HMS-HCD-HMSn, HMS-HMSn

Instrument Group:      Mass spectrometryLiquid Chromatography-Mass Spectrometry, High Resolution Mass Spectrometry

                                      High-Energy Collision-Induced Dissociation

Topic Areas:                OmicsProteomics

 

Explore this capability and more at EMSL's Omics & Mass Spectrometer (MS) resources page under Omics and Mass Spectrometry for Bottom-Up Proteomics. For a list of complimentary mass spectrometry data process software and analytical workflows, visit https://zenodo.org/communities/pnnl

 

Acknowledgements

This work was supported in part by the Earth and Biological Sciences Directorate (EBSD) at Pacific Northwest National Laboratory (PNNL), a multiprogram national laboratory managed by the Battelle Memorial Institute, operating under the U.S. Department of Energy (DOE) contract DE-AC05-76RL01830. User capabilities described here reflect collaborations with the Environmental Molecular Sciences Laboratory (EMSL), a DOE Office of Science (SC-3) user facility operating under the Contract No. DE-AC05-76RL01830.

Terms of Use

Scientists who publish results of research using EMSL resources, capabilities, and resulting data are required to include an acknowledgment of EMSL Policies in any publications. Learn more about user facility data management resources at the Office of Science Program page.

Projects (7)

NIAID Omics-Lethal Human Virus Systems Biology Collection The Omics-LHV Systems Virology project was one of four projects, funded by the NIAID Systems Biology for Infectious Diseases Research Systems Biology Program (funded from 2008-2013), was established in developing and validating predictive...

  1. Datasets

    11

Omics-Lethal Human Virus Computational Modeling & Omics Core Processed Data Collection The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host Responses to Understand Severe Human Virus Infections" (U19AI106772) program project was a comprehensive and interactive systems...

  1. Datasets

    50

The Phenotypic Response of the Soil Microbiome to Environmental Perturbations Project (Soil Microbiome) at Pacific Northwest National Laboratory is a Genomic Sciences Program Science Focus Area (SFA) Project operating under the Environmental Microbiome Science Research Area. The Soil Microbiome SFA...

  1. Datasets

    13

Omics-LHV Profiling of Host Response to Influenza A Virus Infection The OMICS-LHV project aimed to develop a comprehensive understanding of the host response to unique viruses that cause lethal infections in humans by using a systems biology approach, assembling a multidisciplinary team of...

  1. Datasets

    9

Omics-LHV Systems Biology Modeling Host Response to Severe Acute Respiratory Syndrome (SARS) Infection The Systems Virology project was one of four systems biology contracts funded by the NIAID Systems Biology for Infectious Diseases Research Program from 2008-2013. The Systems Biology for...

  1. Datasets

    11

Omics-LHV Profiling of Host Response to West Nile Virus Infection The OMICS-LHV project aimed to develop a comprehensive understanding of the host response to unique viruses that cause lethal infections in humans by using a systems biology approach, assembling a multidisciplinary team of researchers...

  1. Datasets

    14
The Biomedical Resilience & Readiness in Adverse Operating Environments (BRAVE) Project develop new capabilities to improve health and performance of first responders in adverse operating environments common to national defense. The BRAVE project analyze biological samples, collect physiological...
  1. Datasets

    1
Datasets (3)
Publications (1)
Arunima Bhattacharjee
Lindsey N. Anderson
Dr William C Nelson
Ari Jumpponen
Janet K. Jansson
Kirsten Hofmockel
Dr Christopher R Anderton
People (1)

Lindsey Anderson’s research has been dedicated to the identification and characterization of novel, targeted and non-targeted, functional metabolic interactions using a high-throughput systems biology and computational biology approach. Her expertise in functional metabolism and multidisciplinary...

Methods (1)
Software (1)
Resources (1)