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Pending Review Microbiomes contribute to multiple ecosystem services by transforming organic matter in soil. Extreme shifts in the environment, such as drying-rewetting cycles during drought, can impact microbial metabolism of organic matter by altering their physiology and function. These...

The rhizosphere represents a dynamic and complex interface between plant hosts and the microbial community found in the surrounding soil. While it is recognized that manipulating the rhizosphere has the potential to improve plant fitness and health, engineering the rhizosphere microbiome through...

Agriculture is the largest source of greenhouse gases (GHG) production. Conversion of nitrogen fertilizers into more reduced forms by microbes through a process known as biological nitrification drives GHG production, enhances proliferation of toxic algal blooms, and increases cost of crop...

A major challenge in biotechnology and biomanufacturing is the identification of a set of biomarkers for perturbations and metabolites of interest. Here, we develop a data-driven, transcriptome-wide approach to rank perturbation-inducible genes from time-series RNA sequencing data for the discovery...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to West Nile Virus Infection Background West Nile virus ( WNV ) belongs to the mosquito-borne Flaviviridae family and is classified as a Category A priority pathogen by the National Institute of Allergy and...

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Last updated on 2023-02-23T19:37:46+00:00 by LN Anderson PerCon SFA Project Publication Experimental Data Catalog The Persistence Control of Engineered Functions in Complex Soil Microbiomes Project (PerCon SFA) at Pacific Northwest National Laboratory ( PNNL ) is a Genomic Sciences Program...

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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...

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Bruker Daltonics SolariX Magnetic Resonance Mass Spectrometry (MRMS) instruments are available for different magnetic field strengths of 7T, 12T and 15T. The SolariX XR and 2xR instruments use magnetron control technology and a newly developed, high sensitivity, low noise preamplifier to exploit...

The Thermo Scientificâ„¢ Q Exactiveâ„¢ GC hybrid quadrupole Orbitrap Mass Spectrometer provides an unmatched combination of sensitivity, mass-accuracy and resolving power in a single analysis for the highest confidence in compound discovery, identification, and quantitation. With best-in-class...

Last updated on 2023-04-24T18:38:03+00:00 by LN Anderson Instrument Data Source Profile Instrument Name: Agilent DNA Microarray Scanner Model: G25025C Data Type: Microarray hybridisation data (mRNA, miRNA) Method Taxon: Expression profiling by array, Non-coding RNA profiling by array Topic Areas...

Biography Young-Mo Kim is a senior bioanalytical chemist at PNNL. He received his PhD from Pohang University of Science and Technology in the School of Environmental Science and Engineering, studying analysis of metabolites during the bacterial and fungal degradation of xenobiotic substrates using...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment IM101 The purpose of this experiment was to evaluate the host mouse response to Influenza A virus (subtype H5N1) wild-type strain Influenza A/Vietnam/1203/2004, Influenza A/Vietnam/1203/2004 mutant strains PB2-627E...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EU937001 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) and mutant virus infection. Samples were obtained from human histiocytic lymphoma cells...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EHUH001 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) and mutant virus infection. Samples were obtained from human hepatoma carcinoma cells (HUH-7)...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson West Nile Virus Experiment WCT001 The purpose of this experiment was to evaluate the host responseto West Nile virus (WNV-NY99) wild-type (strain 382) and mutant 382-E218A 2 nt virus infection. Sample data was obtained from mouse (strain C57BL...