The Diabetes Autoimmunity Study in the Young (DAISY) seeks to find environmental factors that can trigger the development of type 1 diabetes (T1D) in children. DAISY follows children with high-risk of developing T1D based on family history or genetic markers. Genes, diets, infections, and...

Machine learning is a core technology that is rapidly advancing within type 1 diabetes (T1D) research. Our Human Islet Research Network (HIRN) grant is studying early cellular response initiating β cell stress in T1D through the generation of heterogenous low- and high-throughput molecular...

Neisseria gonorrhoeae is a Gram-negative diplococcus that is responsible for the sexually transmitted infection gonorrhea, a high morbidity disease in the United States and worldwide. Over the last several years N. gonorrhoeae strains resistant to antibiotics used to treat this infection have begun...

The VAST Challenge 2019 presents three mini-challenges and a grand challenge for you to apply your visual analytics research and technologies to help a city grapple with the aftermath of an earthquake that damages their nuclear power plant. These challenges are open to participation by individuals...

This data is a model of synthetic adversarial activity surrounded by noise and was funded by DARPA. The various versions include gradually more complex networks of activities. This data was generated by PNNL. Activities can be phone calls, transactions, or any other type of communications. Most of...

PNNL’s Vision Statement for Equity in the Power Grid Drawing from a wealth of interdisciplinary research in grid modernization, PNNL is spearheading an effort to advance equity and energy justice through the role of scientific research with the goal of building an advanced national power grid...

Predictive Phenomics is addressing the grand challenge of understanding and predicting phenotype by identifying the molecular basis of function and enable function-driven design and control of biological systems .

Education: University of California-Berkeley, PhD Plant Biology University of California-Davis, BS Plant Biology Publications: 2020 Naylor D.T., S.J. Fansler, C.J. Brislawn, W.C. Nelson, K.S. Hofmockel, J.K. Jansson, and R.S. McClure. 2020. "Deconstructing the Soil Microbiome into Reduced-Complexity...

PNNL Publications 2020 Smith J.N., K.J. Tyrrell, J.P. Smith, J.P. Smith, K.K. Weitz, and W.D. Faber. 2020. "Linking Internal Dosimetries of the Propyl Metabolic Series in Rats and Humans Using Physiologically Based Pharmacokinetic (PBPK) Modeling." Regulatory Toxicology and Pharmacology 110. PNNL...

PNNL Publications 2020 Ogden A.J., T.W. Wietsma, T.E. Winkler, Y. Farris, G.L. Myers, and A. Ahkami. 2020. "Dynamics of Global Gene Expression and Regulatory Elements in Growing Brachypodium Root System." Scientific Reports 10. PNNL-SA-145907. doi:10.1038/s41598-020-63224-z 2019 Boiteau R.M., S.J...

Michelle Davison is a microbiologist with a love of challenging, creative, and multidisciplinary projects. She is interested in the role phage play in environmental systems, as well as the myriad ways they can be harnessed as tools. She has experience isolating, developing and working with non-model...

The Human Islet Research Network (HIRN) is a large consortia with many research projects focused on understanding how beta cells are lost in type 1 diabetics (T1D) with a goal of finding how to protect against or replace the loss of functional beta cells. The consortia has multiple branches of...

Publications: 2018 Khan NE, Y Maezato, RS McClure, CJ Brislawn, JM Mobberley, NG Isern, WB Chrisler, LM Markillie, BM Barney, HS Song, WC Nelson, and HC Bernstein. 2018. "Phenotypic responses to interspecies competition and commensalism in a naturally-derived microbial co-culture." Scientific...

Biography Bobbie-Jo Webb-Robertson has 20 years of experience in the statistics and data science fields. She currently serves as the chief scientist of computational biology in the Biological Sciences Division at PNNL. Her research portfolio is largely related to the biomedical field and primarily...

Short Biography Caroline (Carrie) Harwood received her Ph.D. in microbiology from the University of Massachusetts and completed postdoctoral work at Yale University. She held academic appointments at Cornell University and the University of Iowa before moving to the University of Washington in 2005...