Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EIHH001 This experiment evaluated Immortalized Human Hepatocyte ( IHH ) cell line host response to wild-type Ebola viruses Zaire Ebola (ZEBOV '76) and Reston Ebola (REBOV '08) viral infection. Processed Transcriptome...
Last updated on 2023-01-30T00:09:57+00:00 by LN Anderson Ebola Virus Experiment EIHH002 This experiment evaluated Immortalized Human Hepatocyte ( IHH ) cell line host response to response to genetically-reconstructed Zaire Ebola virus infection. Processed Transcriptome Data Unavailable
Influenza A Experiment IM104 Processed Omics Data Unavailable This Influenza experiment evaluated mouse lung expression after etoposide treatment and infection with a pandemic H1N1 influenza strain. Related Experimental Data BioProject: PRJNA382278 GEO: GSE97555 (mRNA transcriptome response)...
A major challenge in biotechnology and biomanufacturing is the identification of a set of biomarkers for perturbations and metabolites of interest. Here, we develop a data-driven, transcriptome-wide approach to rank perturbation-inducible genes from time-series RNA sequencing data for the discovery...
HDF5 file containing 10,000 hydraulic transmissivity inputs and the corresponding hydraulic pressure field outputs for a two-dimensional saturated flow model of the Hanford Site. The inputs are generated by sampling a 1,000-dimensional Kosambi-Karhunen-Loève (KKL) model of the transmissivity field...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Interferon-Stimulated Response to Virus Infection Background The human host Interferon ( IFN ) alpha, beta, and gamma participate in the body's natural immune response to lethal virus infection and disease. The...
The Environmental Determinants of Diabetes in the Young (TEDDY) study is searching for factors influencing the development of type 1 diabetes (T1D) in children. Research has shown that there are certain genes that correlate to higher risk of developing T1D, but not all children with these genes...
The Diabetes Autoimmunity Study in the Young (DAISY) seeks to find environmental factors that can trigger the development of type 1 diabetes (T1D) in children. DAISY follows children with high-risk of developing T1D based on family history or genetic markers. Genes, diets, infections, and...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to MERS-CoV Virus Infection Background Middle East Respiratory Syndrome coronavirus ( MERS-CoV ), part of the Coronaviridae family, is classified as a Category C priority pathogen by the National Institute...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Ebola Virus Infection Background Ebola virus ( EBOV ) is a high risk biological agent, belonging to the Flaviviridae family, and is classified as a Category A priority pathogen by the National Institute...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background Influenza A virus ( IAV ) is a high risk biological agent belonging to the Orthomyxoviridae family is classified as a Category C priority pathogen by the National...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to West Nile Virus Infection Background West Nile virus ( WNV ) belongs to the mosquito-borne Flaviviridae family and is classified as a Category A priority pathogen by the National Institute of Allergy and...
Machine learning is a core technology that is rapidly advancing within type 1 diabetes (T1D) research. Our Human Islet Research Network (HIRN) grant is studying early cellular response initiating β cell stress in T1D through the generation of heterogenous low- and high-throughput molecular...
Short Biography Caroline (Carrie) Harwood received her Ph.D. in microbiology from the University of Massachusetts and completed postdoctoral work at Yale University. She held academic appointments at Cornell University and the University of Iowa before moving to the University of Washington in 2005...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaCL001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to interferon alpha (IFNα) treatment. Sample data was obtained from human lung adenocarcinoma cells (Calu-3)...